Results 101 to 110 of about 711,467 (262)

Unraveling the Metabolic Influence of Olfactory Receptors in Cancer Cells

Sensory Neuroscience, EarlyView.
ORs are aberrantly expressed in various tumor types and regulate cancer cell metabolism through nonclassical signaling pathways, including PI3K/Akt, MAPK, and ERK. These receptors influence tumor proliferation, invasion, and immune evasion. Specific OR–ligand interactions offer promising opportunities for targeted cancer therapy and early diagnosis ...
Chengzhilin Li, Xiaochen Gao, Ziheng Liu, Nianlei Zhang, Xue Cao, Wenwen Qi, Chengcheng Liu   +6 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Carcinoid daganatok [PDF]

, 2010
The authors review the most important clinical aspects of carcinoid tumors. Carcinoid tumors originating in neuroendocrine cells are rare, usually slowly-growing neoplasms, however, they may present as aggressive and rapidly progressing tumors ...
Bodoky, György, Pregun, István, Rácz, Károly, Tulassay, Zsolt   +3 more
core   +2 more sources

Imaging in carcinoid heart disease [PDF]

Cardiologia Croatica, 2013
Carcinoid tumours are rare malignant tumours arising from the neural crest amine precursor uptake and decarboxylation cells, in particular from those situated in the gastrointestinal tract. These tumours are slow growing and indolent, but when they metastasise to the liver, their vasoactive products (5-hydroxytryptamine or serotonin, histamine ...
Ranka Štern Padovan, Maja Hrabak Paar, Josip Vincelj, Mislav Klobučić   +3 more
openaire   +2 more sources

Revisiting tricuspid regurgitation: Historical insights and emerging research perspectives

European Journal of Clinical Investigation, EarlyView.
Tricuspid regurgitation (TR), once seen as benign, is now recognized as a serious and increasingly prevalent condition linked to aging and better imaging. Its association with greater morbidity and mortality has shifted clinical perspectives towards early diagnosis and intervention.
Claudia Gonzalez‐Cucharero, Gemma Vilahur, Marta Saura, Rocío Hinojar, Jose L. Zamorano, Carlos Zaragoza   +5 more
wiley   +1 more source

Carcinoid heart disease: A pictorial report

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2017
Carcinoid tumors are rare, mostly seen in gastrointestinal tract and bronchus. Carcinoid heart disease occurs in up to half of these patients with characteristic involvement of right-sided valves.
Amit Kumar, Bharat Bansal, Raj Kumar, Rahul Mehrotra   +3 more
doaj   +1 more source

ECHOCARDIOGRAPHIC DIAGNOSTICS OF CARCINOID HEART DISEASE

Zdravniški Vestnik, 2002
Background. Carcinoid heart disease is a rare heart disease which affects endocard and heart valves on the right side of heart. It affects only patients with manifested carcinoid syndrome, which is thought to be the consequence of secretory active ...
Janez Ravnik, Maja Podlesnik, Saša Markovič, Mirta Koželj   +3 more
doaj  

Atrial‐secondary tricuspid regurgitation: a better prognosis in early stage heart failure, but not in late stage

ESC Heart Failure, Volume 12, Issue 5, Page 3435-3443, October 2025.
Atrial TR as more favourable prognosis except in advanced patients. Abstract Background and Aims Although the classification of secondary tricuspid regurgitation (STR) by atrial or ventricular aetiology (A‐STR or V‐STR) carries prognostic importance, the confounding effects of New York Heart Association (NYHA) class have not yet been elucidated.
Corentin Bourg, K. Charlotte Lee Frost, Augustin Coisne, Elizabeth Curtis, Guillaume L'official, Yoan Lavie‐Badie, Léo Lemarchand, Julien Dreyfus, Emmanuel Oger, Erwan Donal   +9 more
wiley   +1 more source

The use of octreotide in pediatric patients: Practical applications for gastrointestinal disorders and beyond: A narrative review

Nutrition in Clinical Practice, Volume 40, Issue 5, Page 1040-1052, October 2025.
Abstract Somatostatin is a naturally occurring polypeptide hormone that exerts its effect on the gastrointestinal tract by reducing exocrine and endocrine secretion, resulting in decreased motility, gastric emptying, splanchnic blood flow, fat absorption, lymphatic flow, and gallbladder contraction.
Bailey Dunn, Megan Foxe, Kathy Hunter Sprott, Jessica E. Hook, Candi Jump   +4 more
wiley   +1 more source

Association rule mining of clinical and biomarker data in neuroendocrine tumors: A prospective study on disease progression

Journal of Neuroendocrinology, Volume 37, Issue 10, October 2025.
Abstract There is an unmet need for new methods to predict disease course in patients with neuroendocrine tumors (NET). We investigated 92 putative cancer‐related plasma proteins including chromogranin A (CgA) and clinical parameters at the time of diagnosis to identify early factors associated with progressive (PD) or stable disease (SD).
Ulrich Peter Knigge, Magnus Kjellman, Henning Grønbæk, Espen Thiis‐Evensen, Camilla Schalin‐Jäntti, Staffan Welin, Halfdan Sørbye, Maria del Pilar Schneider, Roger Belusa, The Nordic NET Biomarker Group   +9 more
wiley   +1 more source