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Update in carcinoid heart disease - the heart of the matter
Reviews in Endocrine and Metabolic Disorders, 2021Carcinoid heart disease (CHD) is a paraneoplastic cardiac manifestation occurring in patients with carcinoid syndrome (CS) and advanced neuroendocrine malignancy. In about 20-40% of patients with CS, chronic exposure to tumor-released circulating vasoactive peptides typically results in right-sided valvular fibrosis leading to valve dysfunction and ...
Kira Oleinikov +4 more
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Archives of Internal Medicine, 1984
To the Editor. —We read with interest the case report by Kessler 1 in the August 1983Archivesof a patient with carcinoid heart disease. Kessler stated that "hindgut carcinoids, comprising the descending colon and rectum, frequently metastasized but demonstrated no evidence of endocrine activity." 1(p1615) Exceptions exist on that rule.
Herman De Cock +3 more
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To the Editor. —We read with interest the case report by Kessler 1 in the August 1983Archivesof a patient with carcinoid heart disease. Kessler stated that "hindgut carcinoids, comprising the descending colon and rectum, frequently metastasized but demonstrated no evidence of endocrine activity." 1(p1615) Exceptions exist on that rule.
Herman De Cock +3 more
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Circulation, 1997
A 37-year-old black woman presented with watery diarrhea, facial flushing, and progressive right heart failure. CT-guided biopsy of a liver mass revealed a neuroendocrine tumor. Elevated levels of 5-hydroxyindoleacetic acid confirmed the diagnosis of metastatic carcinoid syndrome. A …
Maher M. Nasser +2 more
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A 37-year-old black woman presented with watery diarrhea, facial flushing, and progressive right heart failure. CT-guided biopsy of a liver mass revealed a neuroendocrine tumor. Elevated levels of 5-hydroxyindoleacetic acid confirmed the diagnosis of metastatic carcinoid syndrome. A …
Maher M. Nasser +2 more
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Carcinoid Heart Disease: an Update
Scandinavian Journal of Gastroenterology, 2002Carcinoid tumours are a poorly defined collection of lesions, histopathologically indistinguishable from gastroentero-pancreatic neuroendocrine tumours. In this report, we discuss epidemiology and survival, clinical presentation, carcinoid valvular heart disease (CVHD), histopathological considerations and treatment options.Review and update of the ...
B. G. Taal +2 more
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Cardiology Clinics, 2019
Carcinoid heart disease is the collective term for all cardiac manifestations that develop in patients with carcinoid. The cardiac manifestations of carcinoid tumors are attributed to the paraneoplastic effects of vasoactive substances released by the malignant cells.
Daniel C. Perry, Salim S. Hayek
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Carcinoid heart disease is the collective term for all cardiac manifestations that develop in patients with carcinoid. The cardiac manifestations of carcinoid tumors are attributed to the paraneoplastic effects of vasoactive substances released by the malignant cells.
Daniel C. Perry, Salim S. Hayek
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1986
Although the carcinoid syndrome was first reported during the nineteenth century, it remains a rare entity. Merling described a tumor of the appendix that was probably carcinoid, while Langhans in 1867 documented a case microscopically.1 The theory that the crypt of Lieberkuhn is the origin of this lesion is credited to Lubarsch.
Neil E. Strickman, Robert J. Hall
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Although the carcinoid syndrome was first reported during the nineteenth century, it remains a rare entity. Merling described a tumor of the appendix that was probably carcinoid, while Langhans in 1867 documented a case microscopically.1 The theory that the crypt of Lieberkuhn is the origin of this lesion is credited to Lubarsch.
Neil E. Strickman, Robert J. Hall
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The cardiac disease associated with the carcinoid syndrome (carcinoid heart disease)
The American Journal of Medicine, 1964Abstract The clinical and pathologic features of seventeen patients with the carcinoid syndrome are reviewed. Nine had carcinoid heart disease. The only clinical feature which distinguished those patients with carcinoid heart disease from those without was the presence of a precordial systolic murmur suggestive of tricuspid regurgitation or pulmonic ...
William C. Roberts, Albert Sjoerdsma
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Carcinoid heart disease: Diagnosis and management
Best Practice & Research Clinical Endocrinology & Metabolism, 2016Hedinger syndrome refers to carcinoid valvular heart disease. The disease is believed to be triggered by vasoactive substances that result in valvular fibrosis. It classically occurs in patients with metastatic carcinoid and preferentially involves the right sided cardiac valves.
Luis, Sushil A., Pellikka, Patricia A.
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Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021Mitchell H Rosner +2 more
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