Results 81 to 90 of about 690,170 (210)

Antagonism of 5‐HT7 Receptors as a Promising Target for Gastric Cancer via Apoptotic Pathway

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.
Antagonism of 5‐HT7 receptors as an approach for combating gastric cancer through the apoptotic pathway is targeted. The present study aims to unearth potential avenues for advanced therapeutic strategies in the battle against this devastating disease by exploring the intricate interactions between 5‐HT7 receptors and gastric cancer, as well as ...
Irfan Cinar, Busra Dincer, Elif Cadirci, Salih Kara, Mehmet Ilhan Yildirgan, Zekai Halici, Saziye Sezin Palabiyik‐Yucelik   +6 more
wiley   +1 more source

ECHOCARDIOGRAPHIC DIAGNOSTICS OF CARCINOID HEART DISEASE

Zdravniški Vestnik, 2002
Background. Carcinoid heart disease is a rare heart disease which affects endocard and heart valves on the right side of heart. It affects only patients with manifested carcinoid syndrome, which is thought to be the consequence of secretory active ...
Janez Ravnik, Maja Podlesnik, Saša Markovič, Mirta Koželj   +3 more
doaj  

Carcinoid heart disease: A pictorial report

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2017
Carcinoid tumors are rare, mostly seen in gastrointestinal tract and bronchus. Carcinoid heart disease occurs in up to half of these patients with characteristic involvement of right-sided valves.
Amit Kumar, Bharat Bansal, Raj Kumar, Rahul Mehrotra   +3 more
doaj   +1 more source

Diagnosis and Treatment of Primary Tracheobronchial Tumors

Cancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background Primary tracheobronchial tumors (PTBTs) are rare but life‐threatening, accounting for approximately 0.2% of all respiratory neoplasms. Owing to their nonspecific clinical symptoms, PTBTs are often initially misdiagnosed as bronchial asthma or bronchitis in the early stages.
Chen Shu, Yu‐jian Liu, Kai‐fu Zheng, Xi‐yang Tang, Meng‐chao Li, Yang Shen, Yu‐long Zhou, Wei‐guang Du, Nan Ma, Jin‐bo Zhao   +9 more
wiley   +1 more source

Management of Cardiac Implantable Electronic Devices in Patients With Severe Symptomatic Tricuspid Regurgitation—Proposed Algorithm and Selected Case Examples

Catheterization and Cardiovascular Interventions, Volume 105, Issue 6, Page 1395-1406, May 1, 2025.
ABSTRACT Severe tricuspid regurgitation (TR) is associated with significant morbidity and mortality. Management of severe TR includes treatment of the underlying cause(s), medical therapy and less commonly surgical tricuspid valve repair. Newer transcatheter tricuspid valve repair devices show promise for those patients who remain symptomatic with ...
Mina M. Kerolos, Kevin Lee, David M. Najman, Mark D. Metzl, Mark J. Ricciardi   +4 more
wiley   +1 more source

Endoscopic findings and outcomes of gastric mucosal changes relating to potassium‐competitive acid blocker and proton pump inhibitor therapy

DEN Open, Volume 5, Issue 1, April 2025.
Abstract Gastric mucosal changes associated with long‐term potassium‐competitive acid blocker and proton pump inhibitor (PPI) therapy may raise concern. In contrast to that for PPIs, the evidence concerning the safety of long‐term potassium‐competitive acid blocker use is scant.
Satoshi Shinozaki, Hiroyuki Osawa, Yoshimasa Miura, Hiroaki Nomoto, Hirotsugu Sakamoto, Yoshikazu Hayashi, Tomonori Yano, Edward J. Despott, Hironori Yamamoto   +8 more
wiley   +1 more source

A Rare Case of Carcinoid Constrictive Pericarditis

JACC: Case Reports, 2020
We describe a case of atypical carcinoid heart disease. A 62-year-old woman with well-differentiated neuroendocrine tumor metastatic to the liver and lymph nodes presented with recurrent unilateral pleural effusions and lower extremity edema ...
Teresa S. Wang, MD, Emily K. Bergsland, MD, Ruth Zhang, MD, Kai Ihnken, MD, Kirsten Tolstrup, MD   +4 more
doaj  

Therapeutic targeting of TGF‐β in lung cancer

The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.
Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi, Amir Barzegar Behrooz, Marco Cordani, Niloufar Rahiman, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Stephen Pistorius, Seyedeh Hoda Alavizadeh, Nima Taefehshokr, Saeid Ghavami   +9 more
wiley   +1 more source

Experiences and Fundamental Care Needs in Patients With Small Intestinal Neuroendocrine Tumours—An Interview Study in a Surgical Context

Journal of Advanced Nursing, Volume 81, Issue 4, Page 2061-2071, April 2025.
ABSTRACT Aims The study aimed to describe patients' fundamental care needs and their experiences of nursing care, throughout surgical treatment of small intestinal neuroendocrine tumours. Design A qualitative descriptive study was performed. Methods Patients' interviews (n = 19) were conducted in Sweden from May 2021 to January 2022 and analysed using ...
Frida Olsson, Eva Jangland, Katarina Edfeldt   +2 more
wiley   +1 more source

Comprehensive transcriptome, miRNA and kinome profiling identifies new treatment options for personalized lung cancer therapy

Clinical and Translational Medicine, Volume 15, Issue 3, March 2025.
Kinase inhibition–based therapies are recommended for a small subset of LC patients with driver mutations. Through enabling technologies and bioinformatics, we demonstrate the potential of KI‐based therapies based on the patient specific needs. Thus, most LC patients become eligible for such treatment algorithms.
Shen Zhong, Yvonne Börgeling, Patrick Zardo, Danny Jonigk, Jürgen Borlak   +4 more
wiley   +1 more source