The architecture of co-culture spheroids regulates tumor invasion within a 3D extracellular matrix [PDF]
arXiv, 2020 Tumor invasion, the process by which tumor cells break away from their primary tumor and gain access to vascular systems, is an important step in cancer metastasis. Most current 3D tumor invasion assays consisted of single tumor cells embedded within an extracellular matrix (ECM). These assays taught us much of what we know today on how key biophysical
arxiv
Breast metastasis and lung large-cell neuroendocrine carcinoma: first clinical observation [PDF]
, 2017 The lung Large-cell neuroendocrine carcinoma (LCNEC) is a very rare aggressive neuroendocrine tumor with a high propensy to metastasize and very poor prognosis.
Di Cristofano, C +8 more
core +1 more source
Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women
Clinical Endocrinology, EarlyView.ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan +14 more
wiley +1 more source
Primary Carcinoid Tumor of the Testis: A Case Report and Review of the Literature
Case Reports in Urology, 2018 Carcinoid tumors usually arise in the gastrointestinal tract. Immunocytohistochemical and radiologic studies are important in detecting the primary tumor site.
Rawad Abou Zahr +5 more
doaj +1 more source
Rigorous results of limiting behaviors of total tumor size under cyclic intermittent therapy for the system of reversible phenotype-switchable tumor cells [PDF]
arXiv, 2023 We are keenly interested in finding the limiting behaviors of total tumor size when tumor cells are subject to the periodic repetition of therapy and rest periods, called intermittent cyclic therapy. We hypothesize that each tumor cell can take either therapy-sensitive or therapy-tolerant phenotype, its phenotype transition is mainly driven by the ...
arxiv
Digestive Endoscopy, EarlyView.Objectives Lymph node metastasis (LNM) is crucial in determining treatment strategies for gastric neuroendocrine tumors (gNETs). While type 3 is considered more aggressive than types 1 and 2 within the clinical subtype of gNETs, the supporting data were insufficient, due to their rarity. We aimed to study the prevalence and risk factors associated with
Yohei Ogata +9 more
wiley +1 more source
FGFR2 amplification in colorectal adenocarcinoma [PDF]
, 2017 FGFR2 is recurrently amplified in 5% of gastric cancers and 1%–4% of breast cancers; however, this molecular alteration has never been reported in a primary colorectal cancer specimen.
Carter, Jamal H +6 more
core +2 more sources
The impact of re‐characterizing metastatic pancreatic neuroendocrine tumors: A prospective study
Journal of Neuroendocrinology, EarlyView.Abstract The biology of metastatic pancreatic neuroendocrine tumors (panNET) may alter over time. It remains to be defined if, how, and when this patient group should be recommended to re‐evaluate the characteristics of their disease. This prospective single‐center, longitudinal cohort study at Uppsala University Hospital, Sweden (NCT03130205 ...
Kazhan Mollazadegan +9 more
wiley +1 more source
Current Concepts on Gastric Carcinoid Tumors
Gastroenterology Research and Practice, 2012 Gastric carcinoid tumors (GCs) are rare lesions representing less than 10% of carcinoid tumors and less than 1% of all stomach neoplasms. There are three distinct types of gastric carcinoids; type I includes the vast majority (70–85%) of these neoplasms ...
G. Nikou, T. Angelopoulos
semanticscholar +1 more source
Primary ovarian neuroendocrine tumor arising in association with a mature cystic teratoma: A case report [PDF]
, 2016 Primary ovarian carcinoid tumors are exceptionally rare entities accounting for approximately 0.1% of all ovarian neoplasms. This report describes a primary ovarian neuroendocrine tumor arising in association with a mature cystic teratoma in a 65 year ...
Bosman +14 more
core +2 more sources