Results 41 to 50 of about 12,695 (199)

ADENOID CYSTIC CARCINOMA OF THE BREAST

International Journal of Clinical Practice, 2003
SUMMARYThis study presents a series of eight patients with adenoid cystic carcinoma of the breast, a rare variant of breast cancer with special clinical and radiological characteristics that may lead to clinical misdiagnosis. Diagnosis may be made by core biopsy or fine needle aspiration cytology.
Kontos, M, Fentiman, I S
openaire   +2 more sources

Patterns of Cervical Metastases and Implications for Neck Management in Minor Salivary Gland Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Objectives Minor salivary gland cancer (MiSGC) is a rare and heterogeneous disease, with different degrees of tumor aggressiveness. The scarce data in the literature show that the presence of lymph node metastases (LNMs) negatively impacts the prognosis.
Eduardo Wanderley Estanislau da Costa, Pedro Nicolau‐Neto, Paula Moretz‐Sohn, Bernardo Cacciari Peryassu, Emilson de Queiroz Freitas, Luis Felipe Ribeiro Pinto, Fernando Luiz Dias   +6 more
wiley   +1 more source

Mithramycin inhibits epithelial-to-mesenchymal transition and invasion by downregulating SP1 and SNAI1 in salivary adenoid cystic carcinoma

Tumor Biology, 2017
Mithramycin exhibits certain anticancer effects in glioma, metastatic cerebral carcinoma, malignant lymphoma, chorionic carcinoma and breast cancer. However, its effects on salivary adenoid cystic carcinoma remain unclear.
Jiasu Li, Hongmei Gao, Lingxu Meng, Lin Yin   +3 more
doaj   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, EarlyView.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Optimizing surgical approaches for lacrimal gland adenoid cystic carcinoma to minimize cross-organ invasion [PDF]

International Journal of Ophthalmology
AIM: To evaluate the outcomes of eye-sparing surgery for lacrimal gland adenoid cystic carcinoma and the impact on tumor recurrence and orbital integrity.
Ming-Shen Ma, Ting-Ting Ren, Fu-Xiao Luan, Jing Li, Nan Wang, Yong Tao, Jian-Min Ma   +6 more
doaj   +1 more source

Concurrent breast adenoid cystic carcinoma and primary squamous cell carcinoma: report of a rare case with single institutional case reviews

Surgical and Experimental Pathology, 2020
Background Adenoid cystic carcinoma and primary squamous cell carcinoma are both rare breast neoplasms, which possess drastically different morphological and molecular features as well as distinguishing clinical behaviors and prognosis. Case presentation
Mingfei Yan, Phillip Bomeisl, Hannah Gilmore, Aparna Harbhajanka   +3 more
doaj   +1 more source

Enhancer‐dependent gene regulation in space, time, and malignancies

International Journal of Cancer, EarlyView.
Abstract Control of cell‐type‐specific gene activation requires the coordinated activity of distal regulatory elements, including enhancers, whose inputs must be temporally integrated. Dysregulation of this regulatory capacity, such as aberrant usage of enhancers, can result in malignant transformation of cells.
Belinda Blum, Victoria Dachtler, Angelika Feldmann   +2 more
wiley   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Adenoid cystic carcinoma of the lacrimal gland metastasising to the liver: report of a case

World Journal of Surgical Oncology, 2006
Background Adenoid Cystic Carcinoma of the lacrimal gland is a rare tumour. Their aggressive behaviour, with a high-risk of local recurrence, and late distant spread of the tumour even after aggressive management has been reported.
Pearce Neil W, El-Mahallawi Hanan, Al-Gholmy Mohammed, Hilal Mohammed Abu, Zeidan Bashar A, Primrose John N   +5 more
doaj   +1 more source

Comparative Analysis of Reflectance Confocal Microscopy and Multiphoton Microscopy in Basal Cell Carcinoma Diagnosis

Journal of Biophotonics, EarlyView.
Reflectance confocal microscopy (RCM) enables rapid in vivo visualization of BCC tumor nests and vasculature. Multiphoton microscopy (MPM) quantifies collagen architecture, revealing significant fragmentation in high‐risk subtypes. Their integration enhances diagnostic accuracy and guides personalized treatment selection. ABSTRACT Background Basal cell
Wenwen Zhong, Lingyang Long, Ying Feng, Xiahui Han, Jianxin Chen   +4 more
wiley   +1 more source