Results 31 to 40 of about 239,414 (309)
Adenoid basal cell carcinoma: a rare facet of basal cell carcinoma [PDF]
BMJ Case Reports, 2016 Basal cell carcinoma (BCC) is a common, locally invasive epithelial malignancy of skin and its appendages. Every year, close to 10 million people get diagnosed with BCC worldwide. While the histology of this lesion is mostly predictable, some of the rare histological variants such as cystic, adenoid, morpheaform, infundibulocystic, pigmented and ...
Kartikay, Saxena +3 more
openaire +2 more sources
Fibroblasts in head neck squamous cell carcinoma associated with perineural invasion have high level nuclear Yes-Associated Protein (YAP) expression [PDF]
, 2015 Paul A. Reynolds, PhD, is supported by the Melville Trust for the Care and cure of Cancer.We retrospectively studied the expression of Yes-associated protein (YAP) using immunohistochemical staining in 10 cases of head and neck squamous cell carcinoma ...
Gersten, Adam +5 more
core +1 more source
Acta Dermato-Venereologica, 2022 Some patients with basal cell carcinoma develop a large number of basal cell carcinomas during their lives. The most common underlying genetic disease that causes multiple basal cell carcinomas is basal cell naevus syndrome. Basal cell naevus syndrome is
Babette J.A. Verkouteren +4 more
doaj +1 more source
Modulatory effects of T-cadherin on cell behavior and growth factor receptor activity in carcinoma cells [PDF]
, 2014 Cancer is a major health problem. Epidermal growth factor receptor (EGFR) pathway plays an important role in cancer progression. EGFR-targeted anti-cancer drugs are being developed to improve anti-cancer therapy.
Maslova, Kseniya
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Difficult-to-treat basal cell cancer: therapeutic possibilities in the era of targeted therapies [PDF]
, 2023 Basal cell carcinoma is a common skin cancer with various risk factors. Treatment options include surgery, chemotherapy, and targeted therapy. HH pathway inhibitors have become integral in managing difficult-to-treat BCC.
Mir Eshghi, Romina
core
Case Reports in Dermatology, 2015 Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Exposure to ultraviolet light is an important risk factor for BCC development and the disorder therefore develops commonly on body areas that are more exposed to sunlight, such as ...
Isil Bulur +3 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
The role of GLI2 in human basal cell carcinoma tumourigenesis [PDF]
, 2010 PhDAbnormal Sonic Hedgehog (SHH) signalling leads to increased transcriptional activation of its downstream effector, GLI2, which is implicated in the pathogenesis of a variety of human tumours, including human basal cell carcinoma (BCC).
Pantazi, Eleni
core
Acta Dermato-VenereologicaBasal cell nevus syndrome is caused by mutations in the Sonic hedgehog pathway and characterized by early-onset basal cell carcinoma. The features of basal cell carcinoma in basal cell nevus syndrome compared with sporadic basal cell carcinoma have not ...
Ching-Ya Wang +12 more
doaj +1 more source