Results 31 to 40 of about 239,171 (309)

Update on Hedgehog Pathway Inhibitor Therapy for Patients with Basal Cell Naevus Syndrome or High-frequency Basal Cell Carcinoma

Acta Dermato-Venereologica, 2022
Some patients with basal cell carcinoma develop a large number of basal cell carcinomas during their lives. The most common underlying genetic disease that causes multiple basal cell carcinomas is basal cell naevus syndrome. Basal cell naevus syndrome is
Babette J.A. Verkouteren, Kelly A.E. Sinx, Marie G.H.C. Reinders, Maureen J.B. Aarts, Klara Mosterd   +4 more
doaj   +1 more source

Vulvar basal cell carcinoma

Indian Journal of Pathology and Microbiology, 2012
Although the basal cell carcinoma (BCC) is the most common malignancy of skin, it is rarely seen in vulva and constitutes 2% to 4% of all vulvar cancers. The cause is unknown but, chronic vulvar irritation is the most important underlying factor.
Mustafa Kara, E Colgecen, Erdogan Nilsen Yildirim   +2 more
doaj   +1 more source

Expression of heparanase in basal cell carcinoma and squamous cell carcinoma [PDF]

Anais Brasileiros de Dermatologia, 2016
: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer.
Maria Aparecida Silva Pinhal, Maria Carolina Leal Almeida, Alessandra Scorse Costa, Thérèse Rachell Theodoro, Rodrigo Lorenzetti Serrano, Carlos D'Apparecida Santos Machado Filho   +5 more
doaj   +1 more source

Pigmented reticular structures in basal cell carcinoma and collision tumours

, 2010
The dermatoscopic diagnosis of basal cell carcinoma (BCC) is based on well-known specific criteria. Despite the fact that a pigment network is considered a negative feature for the diagnosis of BCC, its detection in a BCC context has been reported in 2.8%
Peris, Ketty
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Basal Cell Nevus Syndrome and Sporadic Basal Cell Carcinoma: A Comparative Study of Clinicopathological Features

Acta Dermato-Venereologica
Basal cell nevus syndrome is caused by mutations in the Sonic hedgehog pathway and characterized by early-onset basal cell carcinoma. The features of basal cell carcinoma in basal cell nevus syndrome compared with sporadic basal cell carcinoma have not ...
Ching-Ya Wang, Chun-Bing Chen, Franchesca Marie D. Ilagan, Jing-Yi Lin, Wen-Yi Sung, Lai-Ying Lu, Jau-Yu Liau, Yu-Hsiu Chen, Yi-Hua Liao, Jau-Shiuh Chen, Yi-Shuan Sheen, Yao-Yu Chang, Jin-Bon Hong   +12 more
doaj   +1 more source

Genetic variation in arsenic (+3 oxidation state) methyltransferase (AS3MT), arsenic metabolism and risk of basal cell carcinoma in a European population. [PDF]

, 2014
Exposure to inorganic arsenic increases the risk of basal cell carcinoma (BCC). Arsenic metabolism is a susceptibility factor for arsenic toxicity, and specific haplotypes in arsenic (+3 oxidation state) methyltransferase (AS3MT) have been associated ...
Koppova, K, Vahter, Marie, Broberg Palmgren, Karin, Kumar, Rajiv, Fletcher, T, Engström, Karin S, Broberg, K,, Goessler, W, Engstrom, KS, Koppova, Kvetoslava, Rudnai, Peter, Gurzau, E, Gurzau, Eugen, Goessler, Walter, Leonardi, Giovanni, Leonardi, G, Rudnai, P, Engström, Karin, Vahter, M,, Broberg, Karin, Fletcher, Tony, Kumar, R, Engström, Karin,, Broberg Palmgren, Karin,, Lund University.   +24 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Photobleaching-based autofluorescence mapping reveals distinct patterns in sporadic basal cell carcinoma, nevoid basal cell carcinoma syndrome-associated basal cell carcinoma and squamous cell carcinoma

Frontiers in Medicine
IntroductionAutofluorescence (AF) imaging is a promising non-invasive tool for skin cancer diagnostics. However, AF intensity alone often fails to reliably delineate tumor boundaries due to strong influence from melanin, keratin, vasculature, and surface
Emilija V. Plorina, Ilze Lihacova, Mehdi Boostani, Szabolcs Bozsányi, Norbert Kiss, Norbert Kiss, Dmitrijs Bliznuks, Marta Skrastina, Alexey Lihachev   +8 more
doaj   +1 more source