Cancer Cell of Origin: Spotlight on Luminal Progenitors [PDF]
Does basal type breast cancer arise from oncogenic transformation of a basal cell type? In this issue of Cell Stem Cell, Molyneux et al. (2010) investigate the provenance of the basal-type BRCA1 breast carcinoma and come up with unanticipated ...
Chaffer, Christine L.+1 more
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Background: The placement of a tattoo is a common event. Basal cell carcinoma arising from a tattoo is rare despite this neoplasm being the most common form of skin cancer.
Boya Abudu+3 more
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Subepidermal Basal Cell carcinoma Following Laser Treatment of Congenital Capillary Malformation: A Case Report [PDF]
While basal cell carcinoma is the most common type of skin can- cer in humans, its subepidermal presentation is extremely rare. The risk factors for basal cell carcinoma development are well-known, but it remains unclear in which setting the tumor ...
Brenner, Eva+4 more
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Expression of heparanase in basal cell carcinoma and squamous cell carcinoma [PDF]
: Background: Heparanase is an enzyme that cleaves heparan sulfate chains. Oligosaccharides generated by heparanase induce tumor progression. Basal cell carcinoma and squamous cell carcinoma comprise types of nonmelanoma skin cancer.
Maria Aparecida Silva Pinhal+5 more
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Photosensitizers Imprinting Intracellular Signaling Pathways in Dermato-Oncology Therapy [PDF]
This chapter describes the main deregulated intracellular pathways at both genetic and proteomic levels that are found in three main skin cancers: basal cell carcinoma, squamous cell carcinoma and melanoma. In basal cell carcinoma, the main intracellular
Constantin, Carolina, Neagu, Monica
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Radiation-induced basal cell carcinoma
Background: The treatment of tinea capitis using radiotherapy was introduced at the beginning of the twentieth century. A variety of cancers including basal cell carcinoma (BCC) are seen years after this treatment.
Omid Zargari
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Gorlin syndrome presenting with a unilateral ovarian fibroma in a 22-year-old woman: a case report [PDF]
INTRODUCTION: Nevoid basal cell carcinoma syndrome, or Gorlin syndrome, is an inherited disorder characterized by malignancies of the skin and other organs, skeletal abnormalities, and congenital malformations.
Chitra Pushpanathan+3 more
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HPV infection and immunochemical detection of cell-cycle markers in verrucous carcinoma of the penis [PDF]
Penile verrucous carcinoma is a rare disease and little is known of its aetiology or pathogenesis. In this study we examined cell-cycle proteins expression and correlation with human papillomavirus infection in a series of 15 pure penile verrucous ...
A Ouban+58 more
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TTF-1/p63-positive poorly differentiated NSCLC: A histogenetic hypothesis from the basal reserve cell of the terminal respiratory unit [PDF]
TTF-1 is expressed in the alveolar epithelium and in the basal cells of distal terminal bronchioles. It is considered the most sensitive and specific marker to define the adenocarcinoma arising from the terminal respiratory unit (TRU). TTF-1, CK7, CK5/6,
Barraco N.+8 more
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This study analysed genomic mutations in basal cell carcinoma using whole exome sequencing of DNA specimens obtained from 20 Korean patients. Histological evaluation determined that 15 (75%) were low-risk basal cell carcinomas, and 5 (25%) were high-risk
Hyun Jee Kim+3 more
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