Advanced Science, Volume 13, Issue 8, 9 February 2026.Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang +9 more
wiley +1 more source
Rapid Microfluidic Drug Sensitivity Testing Within 5 Days Using Minimal Clinical Tumor Samples
Advanced Science, Volume 13, Issue 9, 13 February 2026.This study develops the air‐punched fabrication approach for nanoliter‐scale microcavity arrays with ultra‐smooth microcavity surfaces, with which rapid formation and 3D culture of tumor cell spheroids from small numbers of cell samples, as well as high‐throughput drug sensitivity testing can be achieved within 5 days.
Yi‐Xue Chen +11 more
wiley +1 more source
Paraneoplastic cerebellar degeneration from an isolated nodal clear cell carcinoma of suspected gynecologic origin: case report and literature review. [PDF]
J Cancer Res Clin OncolKissinger CR +4 more
europepmc +1 more source
AI‐Enhanced Surface‐Enhanced Raman Scattering for Accurate and Sensitive Biomedical Sensing
Advanced Intelligent Discovery, Volume 2, Issue 1, February 2026.AI‐SERS advances spectral interpretation with greater precision and speed, enhancing molecular detection, biomedical analysis, and imaging. This review explores its essential contributions to biofluid analysis, disease identification, therapeutic agent evaluation, and high‐resolution biomedical imaging, aiding diagnostic decision‐making.
Seungki Lee, Rowoon Park, Ho Sang Jung
wiley +1 more source
Reoperation Versus Dose-Escalated Radiotherapy for Ductal Carcinoma <i>In Situ</i> at the Surgical Margin After Breast-Conserving Surgery for Invasive Ductal Carcinoma. [PDF]
J Breast CancerPark B +8 more
europepmc +1 more source
Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence
Cancer Innovation, Volume 5, Issue 1, February 2026.Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley +1 more source
Inflammatory Presentation of Orbital Metastasis Years after Bilateral Mastectomy for Breast Cancer: A Case Report and Literature Review. [PDF]
Case Rep OphthalmolAhdoot R +3 more
europepmc +1 more source
Potential Targets and Biomarkers of Radionuclide Therapy in Breast Cancer
Cancer Innovation, Volume 5, Issue 1, February 2026.Potential biomarkers for the development of targeted radionuclide therapy that can be employed in the treatment of breast cancer have been summarised in the review. They include receptor markers of ER, PR and HER2, as well as other markers of Trop2, PD‐1, EGFR, GRPR and PSMA.
Yujing Tan +3 more
wiley +1 more source
Prognostic significance of ductal carcinoma <i>in situ</i> coexisting with invasive ductal carcinoma: Biological behavior, immune response and survival outcomes. [PDF]
Mol Clin OncolFedai NK +6 more
europepmc +1 more source