Results 41 to 50 of about 164,586 (302)
Кубанский научный медицинский вестникBackground. Angiogenesis plays a crucial role in the progression of breast cancer. Identifying and investigating the key components of this process, focused on phenotype as well as microenvironment of the tumor, is considered highly relevant for ...
K. A. Aliyev +3 more
doaj +1 more source
Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression [PDF]
, 2010 Breast cancer is the most common cancer among women, and despite significant advances in diagnosing and treating it, metastatic spread of cancer cells results in a high mortality rate. Epithelial-to-mesenchymal transition (EMT) is an embryonic program in
Foubert, Ellen +2 more
core +2 more sources
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
EXPRESSION OF b-HCG IN BREAST TUMORS
The Iraqi Journal of Medical Sciences, 2016 Background: Human chorionic gonadotropin (HCG) is a glycoprotein hormone, which consists of two polypeptide subunits (alpha and beta), produced by syncytial trophoblast cells of the placenta during pregnancy.
Rafal AR Al-Rawi, Faiza AZ Al-Rawi
doaj +4 more sources
Unexpected Metastasis of High Grade Serous Ovarian Cancer to Breast: Case Report and Literature Review [PDF]
, 2016 Introduction: Metastasis of ovarian serous carcinoma to breast and/or axillary lymph nodes represents an unusual event. Nevertheless, their detection and distinction from mammary carcinoma are of huge clinical importance because the treatment and ...
Colagiovanni, V +8 more
core +1 more source
Advanced Science, EarlyView.In the present study, we have demonstrated that the NUP85‐USP47‐ASK1 signaling pathway may have regulated the progression of liver fibrosis through modulating ERS. Additionally, we have developed a CREKA‐coupled liposome to target delivery of MV, a pharmacological inhibitor of NUP85, to activated HSCs, thereby attenuating liver fibrosis. ABSTRACT Liver
Dashuai Yang +11 more
wiley +1 more source
Data in Brief, 2018 Invasive ductal carcinoma is the most common type of breast cancer. Here, we provide a whole transcriptome shotgun sequencing (called RNA-seq) dataset conducted with ten samples of invasive ductal carcinoma tissue and three samples of adjacent normal ...
Ji Hyung Hong, Yoon Ho Ko, Keunsoo Kang
doaj +1 more source
In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors. [PDF]
, 2016 Aberrant Hedgehog (Hh)/glioma-associated oncogene (GLI) signaling has been implicated in cancer progression. Here, we analyzed GLI1, Sonic Hedgehog (Shh) and NF-κB expression in 51 breast cancer (ductal carcinoma) tissues using immunohistochemistry ...
Bei, R. +13 more
core +1 more source
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Diagnostic pitfall in a case of ductal carcinoma-in situ with microinvasion
Journal of Cytology, 2016 We report a case of microinvasive carcinoma of the breast cytologically diagnosed as ductal carcinoma - in situ in an 80-year-old lady with a breast lump. Extensive sampling of mastectomy specimen showed ductal carcinoma in situ (DCIS). Many ducts showed
Yasmin A Momin +3 more
doaj +1 more source