Results 71 to 80 of about 8,035 (221)
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer-induced cardiomyopathy
Cardiomyopathy is one of the characteristic features of cancer. In this study, we establish a suitable model to study breast cancer-induced cardiomyopathy in mice.
Perumal Arumugam Desingu +9 more
core +1 more source
Background. Photodynamic Therapy is one of the treatment methods used in modern oncology. Evaluation of the efficacy in vivo of photosensitizers on tumor models is generally accepted, but the photodynamic therapy technique in mice is not without ...
S. S. Kruglov +9 more
core +1 more source
Background The goal of this study was to explore the inherent antioxidant and antineoplastic activities of methanolic extract of the roots of Hibiscus sabdariffa (MEHSR).
Rumana Yesmin Hasi +5 more
doaj +1 more source
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang +25 more
wiley +1 more source
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang +15 more
wiley +1 more source
Aspects of the Immunological Response to Ehrlich Carcinoma in Mice
Ehrlich Carcinoma cells killed by exposure to ultraviolet light were tested to determine their effectiveness as a vaccine. Mice received injections of 4 x 10^6 vaccine cells subcutaneously in their tails and were later challenged with live tumor cells ...
Fontrier, Toinette
core
The Qa-2 has been described as Human Leucocyte Antigen G (HLA-G) murine homolog. This homology is well accepted to gene and protein structure, in different pathology process and embryos implantation. However, in some neoplasm, this homology is questioned,
Ivy Nayra Nascimento Gonçalves +17 more
core +1 more source
Several biochemical mechanisms, including the arachidonic acid cascade and activation of nicotinic acetylcholine receptors (nAChRs), are involved in increased tumor survival. Combined application of inhibitors acting on these two pathways may result in a
Alexey V. Osipov +6 more
doaj +1 more source
Summary1. When NDV and Ehrlich were mixed at 4°, 25° and 37° and inoculated immediately, a much smaller percentage of tumors grew than in the NAF control mixtures. When the same mixtures were held at 25° or transferred from 4° to 25° for one to 3 hours, inoculation resulted in tumor growth. 2. When virus and tumor were mixed in vivo no tumor inhibitory
A E, MOORE +3 more
openaire +2 more sources

