Results 161 to 170 of about 45,838 (288)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Single-cell analysis unravels divergent gene signatures shaping seminoma stemness and metastasis. [PDF]

Cell Death Discov
Bian Z, Chen B, Guo J, Zhang J, Du G, He S, Yuan H, Zhou Y, Jiang B, Min D, Ye D, Su H, Zhang Y.   +12 more
europepmc   +1 more source

One‐Stone‐Two‐Birds Carrier‐Free Nano‐Cocktail Enables Synergistic Eradication of Cancer Cells/Stem Cells in Breast Cancer Treatment

Exploration, EarlyView.
ABSTRACT Cancer stem cells (CSCs) are widely recognized as the culprits of chemoresistance, tumor metastasis, and relapse. Moreover, most chemotherapeutic drugs not only fail to eliminate CSCs effectively, but also induce the acquisition of stemness characteristics in non‐stem cancer cells. Herein, we propose a cancer cells/CSCs double‐killing modality
Tongyao Zhao, Yao Chen, Haimeng Yuan, Shuqian Yang, Hongyuan Zhang, Yuequan Wang, Shenwu Zhang, Qin Chen, Jin Sun, Zhonggui He, Cong Luo   +10 more
wiley   +1 more source

Primary Embryonal Rhabdomyosarcoma of the Breast: A Case Report and Literature Review. [PDF]

Case Rep Oncol
Al-Bitar A, Aldakak MA, Saifo M.
europepmc   +1 more source

Mediastinal Embryonal Carcinoma [PDF]

, 2020
openaire   +1 more source

EXPRESSION OF E-CADHERIN IN EMBRYOGENETIC INGRESSION AND CANCER INVASION. [PDF]

, 1993
Bracke, Marc, Mareel, Marcus, Vakaet, Luc, Van Roy, Frans   +3 more
core   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

Food Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia, Yuemi Mo, Yuntian Duan, Hu Liang, Yulu Li, Wanruo Wan, Minghuang Luo, Qianhua Li, Xueni Wang, Qing Chen, Zhengcai Du, Xiaotao Hou, Fan Zhang, Jiagang Deng, Erwei Hao   +14 more
wiley   +1 more source

Diagnostic utility of NKX2.2 and CD99 in the central nervous system to distinguish Ewing sarcoma from its mimickers. [PDF]

Acta Neuropathol Commun
Sassi F, Métais A, Varlet P, Berthaud C, Pucelle N, Mandoula M, Dababou Z, Carnes N, Hasty L, Collard A, Chrétien F, Tauziède-Espariat A.   +11 more
europepmc   +1 more source

Fertility Prospects Among Testicular Cancer Survivors: Outcomes of Surgical Sperm Retrieval in Azoospermic Patients. [PDF]

Cureus
Hibi H, Sugie M, Asada Y.
europepmc   +1 more source

Mediastinal embryonal carcinoma

, 2021
openaire   +1 more source