miR-27 negatively regulates pluripotency-associated genes in human embryonal carcinoma cells. [PDF]
PLoS ONE, 2014 Human embryonic stem cells and human embryonal carcinoma cells have been studied extensively with respect to the transcription factors (OCT4, SOX2 and NANOG), epigenetic modulators and associated signalling pathways that either promote self-renewal or ...
Heiko Fuchs +3 more
doaj +1 more source
DNMT3B in vitro knocking-down is able to reverse embryonal rhabdomyosarcoma cell phenotype through inhibition of proliferation and induction of myogenic differentiation [PDF]
, 2016 Aberrant DNA methylation has been frequently observed in many human cancers, including rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children.
Camero, Simona +11 more
core +1 more source
Exploring the interdependencies of research funders in the UK [PDF]
, 2014 Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P +13 more
core +1 more source
Rhabdomyosarcoma: Nose Presenting As Second Primary with Carcinoma Tongue [PDF]
Iranian Journal of Otorhinolaryngology, 2020 Introduction Presence of two primary malignancies is rare and occurs in 3-5% of the cancer patients. As per our extensive internet research, this is the only reported case of a synchronous sino-nasal embryonal rhabdomyosarcoma with squamous cell ...
Devanshu Kwatra +2 more
doaj +1 more source
Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]
, 2015 We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana +2 more
core +4 more sources
Mediastinal mixed germ cell tumor: A case report and literature review
Open Medicine, 2021 Mixed germ cell tumor (MGCT) mainly occurs in young women’s ovaries and men’s testicles and rarely occurs outside the gonad. Fewer than 10 cases of mediastinal MGCT are available in PubMed, Embase, and other databases in English, while mediastinal MGCT ...
Hu Xianwen +4 more
doaj +1 more source
Case Reports in Medicine, 2011 Late relapse of a testicular cancer is an uncommon occurrence. We report a case of late relapse of a testicular tumour combined with a renal cancer and their successful removal with retroperitoneoscopy. The 36-year-old patient underwent left orchiectomy,
Mihály Murányi +4 more
doaj +1 more source
Mixed Germ Cell Tumour in an Infertile Male Having Unilateral Cryptorchidism: A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2016 Mixed germ cell tumours with multiple components occur more frequently than the pure varieties of germ cell tumours. Embryonal carcinoma and teratoma together form the most common components of the mixed germ cell tumour but the yolk sac tumour is ...
Anand Singla +3 more
doaj +1 more source
Rapidly enlarging abdominal mass in a patient with recurrent germ cell tumor
Clinical Case Reports, 2019 This clinical image illustrates the alarming growth rate for an embryonal carcinoma, as well as its highly curable nature. For similar cases, early diagnosis and treatment are key.
Lauren Ho, Louis Pisters, Shi‐Ming Tu
doaj +1 more source
Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma
EMBO Molecular Medicine, 2017 Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components.
Stefania Crippa +9 more
doaj +1 more source