Results 1 to 10 of about 425,718 (285)

Overexpression of Cullin7 is associated with hepatocellular carcinoma progression and pathogenesis

BMC Cancer, 2017
Background Overexpression of Cullin7 is associated with some types of malignancies. However, the part of Cullin7 in hepatocellular carcinoma remains unclear. The aim of this study was to investigate the role of Cullin7 in pathogenesis and the progression
Jun An, Zhigang Zhang, Zhiyong Liu, Ruizhi Wang, Dayang Hui, Yi Jin   +5 more
doaj   +1 more source

Clinical features and diagnostic imaging of cholangiolocellular carcinoma compared with other primary liver cancers: a surgical perspective

Technology in Cancer Research & Treatment, 2020
Background and Objectives: Although cholangiolocellular carcinoma is considered a combined hepatocellular and cholangiocarcinoma, we feel that this classification is not appropriate.
Hiroyuki Takamura PhD, MD, Ryousuke Gabata MD, Yoshinao Obatake PhD, MD, Shinichi Nakanuma PhD, MD, Hironori Hayashi PhD, MD, Kazuto Kozaka PhD, MD, Motoko Sasaki PhD, MD, Mitsuyoshi Okazaki PhD, MD, Takahisa Yamaguchi PhD, MD, Hiroyuki Shimbashi PhD, MD, Shiro Terai PhD, MD, Koichi Okamoto PhD, MD, Isamu Makino PhD, MD, Jun Kinoshita PhD, MD, Keishi Nakamura PhD, MD, Tomoharu Miyashita PhD, MD, Hidehiro Tajima PhD, MD, Itasu Ninomiya PhD, MD, Sachio Fushida PhD, MD, Azusa Kitao PhD, MD, Masaaki Kitahara PhD, MD, Kuniaki Arai PhD, MD, Taro Yamashita PhD, MD, Tatsuya Yamashita PhD, MD, Hiroko Ikeda PhD, MD, Yasunori Satoh PhD, MD, Kenichi Harada PhD, MD, Syuichi Kaneko PhD, MD, Toshihumi Gabata PhD, MD, Tateo Kosaka PhD, MD, Tetsuo Ohta PhD, MD   +30 more
doaj   +1 more source

Advances in the interventional therapy of hepatocellular carcinoma originating from the caudate lobe

Journal of Interventional Medicine, 2022
Hepatocellular carcinoma originating from the caudate lobe, also known as segment I hepatocellular carcinoma, is difficult to treat because of its special location, complex vascular supply, and the proximity of important vessels, bile ducts, and organs ...
Shanmiao Ke
doaj   +1 more source

Enhanced expression of miR-889 forecasts an unfavorable prognosis and facilitates cell progression in hepatocellular carcinoma

Diagnostic Pathology, 2021
Background As a new type of molecular marker, microRNAs (miRNAs) can be used for early diagnosis and prognosis prediction of malignant tumors, and has broad clinical application prospects.
He Wang, Huiwen Wang, Wenyu Cui, Qiao Zhang, Jing Li, Qi Zhang   +5 more
doaj   +1 more source

The activation of the Notch signaling pathway by UBE2C promotes the proliferation and metastasis of hepatocellular carcinoma

Scientific Reports
UBE2C, a ubiquitin-conjugating enzyme, functions as an oncogene in different types of human cancers. Nonetheless, the exact influence of UBE2C on the development of HCC via regulation of ubiquitination remains uncertain.
Ping Zhan, Yuyan Lu, Jing Lu, Yizhe Cheng, Changhong Luo, Fan Yang, Wenqing Xi, Jinzhu Wang, Xuesong Cen, Fuqiang Wang, Chengrong Xie, Zhenyu Yin   +11 more
doaj   +1 more source

Protein arginine N-methyltransferase 1 promotes the proliferation and metastasis of hepatocellular carcinoma cells

Tumor Biology, 2017
Hepatocellular carcinoma is the most common subtype of liver cancer. Protein arginine N-methyltransferase 1 was shown to be upregulated in various cancers.
Qing Gou, ShuJiao He, ZeJian Zhou
doaj   +1 more source

N6-Methyladenosine RNA Methylation Regulators Have Clinical Prognostic Values in Hepatocellular Carcinoma

Frontiers in Genetics, 2020
Although it is widely accepted that N6-methyladenosine (m6A) RNA methylation plays critical roles in tumorigenesis and progression, the values of m6A modification are less known in hepatocellular carcinoma.
Wei Liu, Cuiqing Zhong, Deguan Lv, Mengjie Tang, Feng Xie   +4 more
doaj   +1 more source

Rising plasma nociceptin level during development of HCC: A case report

, 2004
AIM: Although liver cirrhosis is a predisposing factor for hepatocellular carcinoma (HCC), relatively few reports are available on HCC in primary biliary cirrhosis.
Horváth, Andrea, Schaff, Zsuzsa, Aniko Folhoffer, Kornelia Tekes, Szalay, Ferenc, Ferenc Szalay, Hantos, Mónika Beatrix, Tekes, Kornélia, Judit Halász, Folhoffer, Anikó, Illyés, György, Halász, Judit, Andrea Horvath, Peter Laszlo Lakatos, Gyorgy Illyés, Lakatos, Péter László, Monika Beatrix Hantos, Zsuzsa Schaff   +17 more
core   +1 more source

The role of hypoxia-senescence co-related molecular subtypes and prognostic characteristics in hepatocellular carcinoma

Scientific Reports
Hepatocellular carcinoma (HCC) is known for its high invasiveness, high fatality rate. Both hypoxia and senescence play crucial roles in the initiation and progression of cancer, yet their prognostic implications in HCC are yet to be fully understood ...
Fuqing Chen, Yifan Cai, Xiangmei Chen, Changzhou Chen, Qinliang Fang, Jianming Liu, Yibin Zhang, Jianyin Zhou   +7 more
doaj   +1 more source

Exosomal microRNAs in hepatocellular carcinoma

Cancer Cell International, 2021
Hepatocellular carcinoma is one of the most common malignant tumors worldwide and the fourth leading cause of cancer-related deaths. The prognosis of hepatocellular carcinoma patients is extremely poor due to the occult onset and high metastasis of ...
Chenbin Liu, Han Wu, Yinqi Mao, Wei Chen, Shuying Chen   +4 more
doaj   +1 more source