Results 1 to 10 of about 446,465 (267)

Clinical and pathological evaluation of fibrolamellar hepatocellular carcinoma: a single center study of 21 cases [PDF]

open access: yesClinics, 2015
OBJECTIVES: Fibrolamellar hepatocellular carcinoma is a rare primary malignant liver tumor that differs from conventional hepatocellular carcinoma in several aspects.
Aline Lopes Chagas   +10 more
doaj   +9 more sources

Immunohistochemical angiogenic biomarkers in hepatocellular carcinoma and cirrhosis: correlation with pathological features [PDF]

open access: yesClinics, 2016
OBJECTIVE To investigate immunohistochemical markers of angiogenesis and their association with pathological prognostic features in hepatocellular carcinoma and cirrhotic liver.
Osmar Damasceno Ribeiro   +2 more
doaj   +4 more sources

Autophagy-related long non-coding RNA MIR210HG plays a therapeutic role in hepatocellular carcinoma [PDF]

open access: yesDiscover Oncology
Objective This study aimed to investigate the role of the autophagy-related long noncoding RNA (lncRNA) MIR210HG in hepatocellular carcinoma and its potential as a therapeutic target.
Chaoqun Zhang   +6 more
doaj   +2 more sources

CMTM6 promotes hepatocellular carcinoma invasion and metastasis and tumor-associated neutrophil immunoinfiltration through the Wnt/β-catenin pathway [PDF]

open access: yesEuropean Journal of Medical Research
Background CMTM6 has been closely associated with the onset and progression of various tumor types. However, the precise mechanism by which CMTM6 operates in hepatocellular carcinoma remains elusive, necessitating further investigation.
Panpan Kong   +6 more
doaj   +2 more sources

Resveratrol protects against chronic alcohol-induced liver disease in a rat model

open access: yesSTEMedicine, 2022
Hepatic ethanol metabolism participates in the pathogenesis of alcoholic liver disease (ALD). We aimed to evaluate the protecting effects and underlying mechanisms of Resveratrol against ALD.
Hanzhang Zhu   +3 more
doaj   +1 more source

CD58 acts as a tumor promotor in hepatocellular carcinoma via activating the AKT/GSK-3β/β-catenin pathway

open access: yesJournal of Translational Medicine, 2023
Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Chuanzheng Wang   +7 more
doaj   +1 more source

A case of hepatocellular carcinoma recurring during pregnancy [PDF]

open access: yes, 2021
The hepatocellular carcinoma is more common in African and Asian countries with an incidence in women at around 5.5/10,000. Hepatocellular carcinoma is an aggressive tumour, with high recurrence rates, reaching around 50%.
Chatbi, Zaineb   +4 more
core   +2 more sources

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

open access: yesMolecular Oncology, EarlyView., 2023
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela   +2 more
wiley   +1 more source

Heat shock protein HSPA13 promotes hepatocellular carcinoma progression by stabilizing TANK

open access: yesCell Death Discovery, 2023
HSPA13, an important member of the heat shock protein family, plays an essential role in the oncogenesis of many organs, but the mechanism and function in hepatocellular carcinoma (HCC) is still unclear.
Xuesong Cen   +9 more
doaj   +1 more source

β-Lapachone Selectively Kills Hepatocellular Carcinoma Cells by Targeting NQO1 to Induce Extensive DNA Damage and PARP1 Hyperactivation

open access: yesFrontiers in Oncology, 2021
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death globally. Currently there is a lack of tumor-selective and efficacious therapies for hepatocellular carcinoma. β-Lapachone (ARQ761 in clinical form) selectively kill NADPH:
Wenxiu Zhao   +15 more
doaj   +1 more source

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