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Hepatocellular carcinoma [PDF]
Nature Reviews Disease Primers, 2021 Liver cancer remains a global health challenge, with an estimated incidence of >1 million cases by 2025. Hepatocellular carcinoma (HCC) is the most common form of liver cancer and accounts for ~90% of cases. Infection by hepatitis B virus and hepatitis C virus are the main risk factors for HCC development, although non-alcoholic steatohepatitis ...
Llovet, Josep M. +9 more
semanticscholar +5 more sources
Case Report: Long-term disease-free survival in an advanced hepatocellular carcinoma patient: an exceptional response to PD-1 inhibitor therapy. [PDF]
Front ImmunolIntroductionHepatocellular carcinoma (HCC) is a leading cause of cancer-related death, with most patients diagnosed at advanced stages, often precluding surgical resection.
Fang Q +7 more
europepmc +2 more sources
Hepatocellular Carcinoma [PDF]
Current Opinion in Oncology, 2000 Hepatocellular carcinoma (HCC) is a disease that is extremely difficult to manage and is increasing markedly in incidence. This presents both an opportunity and a challenge. At-risk patients can be identified and early detection of HCC is feasible. New surgical techniques and postoperative therapies, including hepatic intra-arterial radiation, may ...
LENCIONI, RICCARDO ANTONIO +2 more
+16 more sources
Hepatocellular carcinoma [PDF]
Current Opinion in Gastroenterology, 2001 The number of papers published regarding hepatocellular carcinoma between 1999 and 2001 increased from previous years. This year a study confirmed the increase in incidence in the United States. Also, several studies established for the first time that tobacco smoking was a risk factor for the development of this tumor. Several studies established that
M M, Chokshi, J A, Marrero
openaire +4 more sources
Journal of Translational Medicine, 2023 Background Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide because of rapid progression and high incidence of metastasis or recurrence.
Chuanzheng Wang +7 more
doaj +1 more source
Resveratrol protects against chronic alcohol-induced liver disease in a rat model
STEMedicine, 2022 Hepatic ethanol metabolism participates in the pathogenesis of alcoholic liver disease (ALD). We aimed to evaluate the protecting effects and underlying mechanisms of Resveratrol against ALD.
Hanzhang Zhu +3 more
doaj +1 more source
AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma.
Hepatology, 2023 for End-Stage Liver Disease;
A. Singal +15 more
semanticscholar +1 more source
Hepatocellular carcinoma [PDF]
Anales del Sistema Sanitario de Navarra, 2016 Liver cancer is the second leading cause of cancer-related deaths globally and has an incidence of approximately 850,000 new cases per year. Hepatocellular carcinoma (HCC) represents approximately 90% of all cases of primary liver cancer. The main risk factors for developing HCC are well known and include hepatitis B and C virus infection, alcohol ...
Llovet, Josep M. +6 more
+9 more sources
Atezolizumab plus Bevacizumab in Unresectable Hepatocellular Carcinoma.
New England Journal of Medicine, 2020 BACKGROUND The combination of atezolizumab and bevacizumab showed encouraging antitumor activity and safety in a phase 1b trial involving patients with unresectable hepatocellular carcinoma. METHODS In a global, open-label, phase 3 trial, patients with
R. Finn +20 more
semanticscholar +1 more source
Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma.
NEJM Evidence, 2022 Tremelimumab/Durvalumab for Hepatocellular CarcinomaThis trial examined overall survival (OS) with tremelimumab plus durvalumab, durvalumab alone, or sorafenib in untreated patients with hepatocellular cancer who were not candidates for locoregional ...
G. Abou-Alfa +30 more
semanticscholar +1 more source