Results 131 to 140 of about 735,902 (298)

Rarely seen rectum tumor with bad prognosis: A case of large cell neuroendocrine carcinoma

open access: yesAmerican Journal of Experimental and Clinical Research, 2014
Large cell neuoendocrine carcinoma forms an extremely aggressive and poor prognostic subset of neuroendocrine tumors with a tendency to early metastasis.
Rojbin Karakoyun   +4 more
doaj  

A rare breast tumor: solid neuroendocrine carcinoma

open access: yes, 2013
A rare breast tumor: solid neuroendocrine carcinoma BACKGROUND: Solid neuroendocrine carcinoma of breast (NECB) is extremely rare. In this paper, we present a case of inflammatory primary solid neuroendocrine carcinoma of breast managed by surgery and ...
Lucchini R   +5 more
core  

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Large Cell Neuroendocrine Carcinoma of the Lung

open access: yes, 1995
We report three cases of neuroendocrine tumors of the lung characterized by large pleomorphic cells with frequent mitosis, which show neuroendocrine differentiation by both light microscopy or electron microscopy and immunohistochemistry.
정우희
core  

Ovarian neuroendocrine carcinoma of metastatic origin: clues for diagnosis

open access: yes, 2019
International audienceNeuroendocrine tumors of the ovary are rare and of uncertain histogenesis. They may be primary or metastatic. Pathogenesis of ovarian carcinomas remains unknown.
Vermesch, Charlotte   +6 more
core   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Harnessing the nonthermal effects of ultrasound for cancer treatment: From mechanisms to applications

open access: yesSmart Molecules, EarlyView.
Nonthermal ultrasound transforms acoustic energy into diverse therapeutic bioeffects through cavitation, mechanical stimulation, and physicochemical activation. This review discusses how acoustic parameters, biological mechanisms, and responsive materials interact to influence nonthermal ultrasound‐enabled cancer therapies. Mechanism‐guided engineering
Liu Wang   +5 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

open access: yesVIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Outcomes in Orbit‐Sparing Versus Orbit‐Sacrificing Surgery for Sinonasal Malignancies With Orbital Involvement: A Systematic Review and Meta‐Analysis

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Sinonasal malignancies with orbital involvement may be managed with orbit‐sacrificing or orbit‐preserving surgical approaches, with a recent shift towards orbital preservation to reduce postoperative morbidity while maintaining oncological success.
Claire Jing‐Wen Tan   +9 more
wiley   +1 more source

Neuroendocrine Carcinoma of the Head and Neck: A Two‐Decade Institutional Experience

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Primary neuroendocrine carcinoma (NEC) of the head and neck is rare (< 1% of cases) and aggressive, with poorly defined management strategies. This study evaluated clinical characteristics, treatment patterns, and survival outcomes in a single‐institution cohort, identifying factors associated with improved survival.
Micah K. Harris   +11 more
wiley   +1 more source

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