Results 171 to 180 of about 735,902 (298)

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma

open access: yesHistopathology, EarlyView.
Frequently positive TROP2 IHC suggests that TROP2 antibody‐drug conjugates may be potential treatments for LCNEC. Introduction TROP2 antibody‐drug conjugates have shown promising anti‐tumour activity, but neither the activity of these agents nor TROP2 expression has been well studied in pulmonary large cell neuroendocrine carcinoma (LCNEC), a rare and ...
Michael Minkley   +6 more
wiley   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

open access: yesHistopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Novel and emerging skin carcinomas and adnexal tumours

open access: yesHistopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec   +2 more
wiley   +1 more source

Primary small-cell neuroendocrine carcinoma of the bladder: a very rare histological subtype. [PDF]

open access: yesOxf Med Case Reports
Mesmoudi S   +10 more
europepmc   +1 more source

Whole‐slide analysis of mitotic activity in melanoma reveals higher‐proliferation hotspots and distinct spatial patterns

open access: yesHistopathology, EarlyView.
Whole‐slide analysis of melanoma identified higher‐proliferation mitotic hotspots than routine pathology assessment and revealed distinct spatial patterns of mitotic organization, highlighting the potential of computational mitosis mapping to provide insights beyond conventional mitotic counting.
Shlomo Tsuriel   +4 more
wiley   +1 more source

Novel and emerging cutaneous soft tissue tumours

open access: yesHistopathology, EarlyView.
This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley   +1 more source

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