Results 311 to 320 of about 689,752 (349)

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

Advanced Science, EarlyView.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui, Ka‐Meng Lei, Yingying Liu, Xinru Huang, Yunlong Zhong, Xiaojun Chen, Mingji Wei, Jie Yan, Ren Shen, Pui‐In Mak, Rui P. Martins, Shuhong Yi, Ping Wang, Yanwei Jia   +13 more
wiley   +1 more source

LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5

Advanced Science, EarlyView.
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li, Zhuo‐Ran Liang, Zhi‐Chao Liu, Xue‐Ping Luo, Jun‐Yi Li, Xiao‐Mei Yu, Xuan‐Zhang Huang, Yan He, Tao‐Yang Xu, Jiao‐Jiao Xu, Shao‐Cong Peng, Yu‐Xiang Song, Yan He, Xiao‐Wan Zhuang, Can‐Can Zheng, Fan Zhang, Alfred King‐Yin Lam, Wei Dai, Ming‐Liang He, Bo Liu, Qi Zhao, Guo‐Liang Lu, Jin‐Bao Liu, Zhen‐Ning Wang, Zhi‐Gang Li, Ze‐Xian Liu, Wen‐Wen Xu, Bin Li   +27 more
wiley   +1 more source

Effect of the number of negative lymph nodes removed on the survival and recurrence rate patients with non-small-cell lung cancer undergoing surgery: A multicenter retrospective cohort study. [PDF]

Medicine (Baltimore)
Bahardoust M, Yarahmadi D, Niroomand B, Rashidi S, Daneshfar F, Haghmoradi M, Goodarzy B, Tizmaghz A.   +7 more
europepmc   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

Prediction model for the early recurrence of stage IA-IIA non-small cell lung cancer based on hematological indexes and imaging features. [PDF]

Discov Oncol
Zhao W, Sun Y, Liu X, Zhang M, Zhu B.
europepmc   +1 more source

Mycophenolate Mofetil for Steroid-Refractory Immune-Related Hepatitis and Sclerosing Cholangitis Following Neoadjuvant Chemoimmunotherapy in Non-Small Cell Lung Cancer: A Case Report. [PDF]

Surg Case Rep
Iguchi H, Kaki T, Harutani Y, Kitahara D, Hirai Y, Kanai K, Hirai I.   +6 more
europepmc   +1 more source

Innovations in modern low-LET radiotherapy regimens for locally advanced non-small cell lung cancer: a meta-analysis and systematic review of high-dose-rate brachytherapy, stereotactic body radiotherapy, and hypofractionated proton therapy. [PDF]

BMC Cancer
Tan M, Li L, Tan B, Yang J.
europepmc   +1 more source

Diagnostic accuracy of serum biomarkers MMP11 and SPP1 in non-small cell lung cancer: an analysis of sensitivity, specificity, and area under the curve. [PDF]

Transl Lung Cancer Res
Yoon ML, Kim SY, Chun H, Park J, Seo WJ, Lee JY, Yoon JH.   +6 more
europepmc   +1 more source

Rectal metastasis from lung cancer diagnosed by endoscopic ultrasound-guided fine needle biopsy: A case report. [PDF]

DEN Open
Mukawa S, Koya Y, Murakami T, Miyagawa K, Maruno Y, Yamaguchi K, Hanada S, Oe S, Harada M.   +8 more
europepmc   +1 more source

Multicenter Retrospective Analysis of Pulmonary Sarcomatoid Carcinoma Clinically Diagnosed Using Small Biopsy Specimens. [PDF]

Cancer Diagn Progn
Inomata M, Tsuda T, Ichikawa T, Matsumoto M, Mizushima I, Azechi K, Takata N, Murayama N, Seto Z, Tokui K, Masaki Y, Okazawa S, Imanishi S, Miwa T, Hayashi R, Taniguchi H.   +15 more
europepmc   +1 more source