Results 281 to 290 of about 1,495,069 (363)

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

Andrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch, Ahmad Kareem, Simon F. Merz, Marc Teckentrup, Alexander Fichtner, Felix Bremmer, Jeannine Missbach‐Guentner   +6 more
wiley   +1 more source

Non-invasive low-grade papillary urothelial carcinoma with whorled features: a report of two cases. [PDF]

Int J Clin Exp Pathol
Madwani K, Moideen P, Toscano MP, Vemavarapu LK, Trzpuc TD, Sharma SJ.   +5 more
europepmc   +1 more source

Multiple Lung Metastases of Papillary Thyroid Carcinoma Detected by Detailed Pathological Examination: A Case Series. [PDF]

Cureus
Yoshino R, Ujiie N, Yasuda S, Kitada M.
europepmc   +1 more source

DysRegNet: Patient‐specific and confounder‐aware dysregulated network inference towards precision therapeutics

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Gene regulation is frequently altered in diseases in unique and patient‐specific ways. Hence, personalised strategies have been proposed to infer patient‐specific gene‐regulatory networks. However, existing methods do not scale well because they often require recomputing the entire network per sample.
Johannes Kersting, Olga Lazareva, Zakaria Louadi, Jan Baumbach, David B. Blumenthal, Markus List   +5 more
wiley   +1 more source

Identification of new small molecules for selective inhibition of SERCA 1 in patient‐derived metastatic papillary thyroid cancer

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Papillary thyroid cancer (PTC) is a general thyroid cancer subtype; however, PTC is associated with metastasis or recurrence via anti‐cancer drug resistance, rendering it practically incurable. Therefore, effective and reliable clinical approaches are urgently required.
Seok‐Mo Kim, Keunwan Park, Hyeok Jun Yun, Jung Min Kim, Kyung Hwa Choi, Ki Cheong Park   +5 more
wiley   +1 more source

TPX2 promotes papillary renal cell carcinoma progression by forming a ceRNA with LINC00894. [PDF]

BMC Med Genomics
Ding Z, Ying W, Yan Y, Zhao Y, Liu C, Ma L.   +5 more
europepmc   +1 more source

GGCT Inhibits Ferroptosis in PTC Cells by Upregulating p53 Through RPS15A

Cancer Science, EarlyView.
Our results showed that γ‐glutamine cyclotransferase (GGCT) knockdown in PTC cells inhibited GSH synthesis, promoted the malignant accumulation of malondialdehyde (MDA) and reactive oxygen species (ROS), and finally promoted cell ferroptosis. In vivo experiments showed that Pro‐GA, a specific inhibitor of GGCT, inhibited the subcutaneous tumorigenesis ...
Hui‐min Zhang, Han‐ning Li, Enbo Qi, Yang Yang, Huiping Ma, Jie Ma, Xiwen Xiong, Jun Wang, Zhi‐fang Yang, Xing‐hua Liao   +9 more
wiley   +1 more source

Intracholecystic papillary neoplasm with associated invasive carcinoma, initially presenting with a palpable mass in the right lower quadrant: A case report. [PDF]

Int J Surg Case Rep
Yonenaga Y, Nitta T.
europepmc   +1 more source

Renaming low risk conditions labelled as cancer [PDF]

, 2018
Barratt, Alexandra, Brito, Juan P., McCaffery, Kirsten, Moynihan, Ray, Nickel, Brooke   +4 more
core   +1 more source

Real‐World Data Analysis of Genomic Alterations Detected by a Dual DNA–RNA Comprehensive Genomic Profiling Test

Cancer Science, EarlyView.
This study analyzed 1356 cases using GenMineTOP, Japan's first dual DNA–RNA CGP test, and identified oncogenic alterations in 91.5% of cases. The RNA panel detected 105 fusion events, including 11 NTRK fusions. Furthermore, the analysis clarified the independent effects of genomic abnormalities and cancer type on RNA expression, providing valuable ...
Kousuke Watanabe, Miho Ogawa, Aya Shinozaki‐Ushiku, Shuichi Tsutsumi, Kenji Tatsuno, Hiroyuki Aburatani, Hidenori Kage, Katsutoshi Oda   +7 more
wiley   +1 more source