Results 71 to 80 of about 83,751 (271)

Hybrid Classic-Quantum Computing for Staging of Invasive Ductal Carcinoma of Breast [PDF]

arXiv, 2023
Despite the great current relevance of Artificial Intelligence, and the extraordinary innovations that this discipline has brought to many fields -among which, without a doubt, medicine is found-, experts in medical applications of Artificial Intelligence are looking for new alternatives to solve problems for which current Artificial Intelligence ...
arxiv  

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

Familial aggregation of bladder cancer [PDF]

Vojnosanitetski Pregled, 2011
Background. Except for smoking and certain occupational exposures, the etiology of bladder cancer is largely unknown. Several case reports have described familial aggregation of transitional cell carcinoma of the bladder.
Ilić Milena, Stojadinović Miroslav, Milosavljević Zoran   +2 more
doaj   +1 more source

Papillary Serous Carcinoma of the Peritoneum

Journal of Obstetrics and Gynaecology, 1995
AbstractObjective: To describe the clinical features of papillary serous carcinoma of the peritoneum followed by a short review of the literature.Methods: From January 1986 to May 1994, six patients with papillary serous carcinoma of the peritoneum were treated at our institution.
Chew, S., Tham, K.F., Lim, F.K., Ratnam, S.S.   +3 more
openaire   +3 more sources

AKT1E17K‐Interacting lncRNA SVIL‐AS1 Promotes AKT1 Oncogenic Functions by Preferentially Blocking AKT1E17K Dephosphorylation

Advanced Science, EarlyView.
Wang et al. discover a novel lncRNA regulator of mutant oncoprotein which prevents AKT1E17K dephosphorylation. SVIL‐AS1 overexpression correlates with poor prognosis of breast cancer patients. It interacts with AKT1E17K protein and impedes PP2A holoenzyme from dephosphorylating AKT1 by blocking the binding of the regulatory subunit PPP2R2A to AKT1 ...
Jingyi Wang, Wenying Chen, Qianying Li, Ruiyi Yang, Xiaorong Lin, Ping Han, Xiaoming Huang, Hai Hu, Man‐Li Luo   +8 more
wiley   +1 more source

Evaluation of the Pharmacokinetic Drug Interaction of Capmatinib With Itraconazole and Rifampicin and Potential Impact on Renal Transporters in Healthy Subjects

The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 228-238, February 2023., 2023
Abstract Capmatinib is a highly specific, potent, and selective mesenchymal–epithelial transition factor inhibitor predominantly eliminated by cytochrome P450 (CYP) 3A4 and aldehyde oxidase. Here, we investigated the effects of a strong CYP3A inhibitor (itraconazole) and a strong CYP3A inducer (rifampicin) on single‐dose pharmacokinetics of capmatinib.
Xiaoming Cui, Xinhui Chen, Nathalie Pognan, Tirtha Sengupta, Gholamreza Rahmanzadeh, Ruediger Kornberger, Monica Giovannini   +6 more
wiley   +1 more source

Concurrence of Papillary Thyroid Carcinoma and Hürthle Cell Carcinoma in an Iranian Woman with Hashimoto's Thyroiditis [PDF]

Iranian Journal of Pathology, 2019
The most usual form of the endocrine carcinoma is thyroid cancer (TC). In addition to papillary thyroid carcinoma (PTC), recent studies revealed incidence of RET/PTC rearrangement in other tumors, like Hürthle cell carcinoma (HCC) and even in non ...
Fatemeh Samiee Rad, Sohayla Farajee, Erfan Torabi   +2 more
doaj   +1 more source

Effect of autonomic nervous system resection extent on urinary dysfunction in robotic rectal cancer surgery

Annals of Gastroenterological Surgery, EarlyView.
In rectal cancer surgery, this study examined the risk factors for urinary dysfunction and the effect of autonomic nervous system resection extent on urinary dysfunction. Autonomic nervous system resection and lateral lymph node dissection were independent risk factors for urinary dysfunction.
Sodai Arai, Hiroyasu Kagawa, Akio Shiomi, Yusuke Yamaoka, Shoichi Manabe, Chikara Maeda, Yusuke Tanaka, Shunsuke Kasai, Akifumi Notsu, Yusuke Kinugasa   +9 more
wiley   +1 more source

Multimodal Deep Learning for Personalized Renal Cell Carcinoma Prognosis: Integrating CT Imaging and Clinical Data [PDF]

arXiv, 2023
Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell carcinoma by integrating CT imaging and clinical data and addressing the limitations observed in prior studies. The aim
arxiv  

Intracystic Papillary Carcinoma of the Breast

Radiology Case Reports, 2009
We present the case of a 63-year-old woman with intracystic papillary carcinoma of the breast who presented with a palpable mass, one year after a negative mammogram. Sonography showed a complex mass and ultrasound-guided aspiration cytology was negative, and the patient returned 6 months later with a recurrent mass. Excisional biopsy revealed invasive
Élan Burton, John A. McKeating, Kurt R. Stahlfeld   +2 more
openaire   +2 more sources