Results 31 to 40 of about 893,300 (260)

Small cell carcinoma of prostate [PDF]

open access: yesPerspectives In Medical Research, 2018
Small cell carcinoma(SCC) of prostate is a very rare and highly aggressive neoplasm which constitutes less than 1 % of all prostate cancers. Half of the small cell carcinomas arising in the prostate are pure without an associated adenocarcinoma ...
Aurobinda S , Archita Mohanty J , Niharika P, Srikanth S
doaj  

Primary small cell carcinoma of the upper urinary tract: A case report

open access: yesUrology Case Reports, 2019
Brief Abstract: Small cell carcinoma of the urinary tract is an aggressive malignancy that comprises less than 1% of urinary bladder cancers. The renal pelvis and ureter, also lined by urothelium, are rare sites for small cell carcinoma.
Veronica Rupert   +5 more
doaj   +1 more source

Primary tracheal small‐cell carcinoma detected 11 months after surgery for pulmonary large‐cell neuroendocrine carcinoma: A case report

open access: yesThoracic Cancer, 2023
Primary tracheal small‐cell carcinoma is rare, and is often treated using small‐cell lung cancer guidelines given that no standard treatment has been established for it.
Chihiro Sugimoto   +15 more
doaj   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Hypercalcemia complicating small-cell carcinoma [PDF]

open access: yesCancer, 1981
Hypercalcemia is a common paraneoplastic syndrome complicating some varieties of lung cancer. It has rarely been reported with small-cell carcinoma of the lung. Seven cases of hypercalcemia complicating small-cell carcinoma of the lung are described; clinical features indicate that significant bone or bone marrow involvement is present in all cases ...
M L, Hayward   +3 more
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Solid ovarian teratoma with carcinoid tumor and small cell neuroendocrine carcinoma in a 68-year-old patient: A case report

open access: yesHuman Pathology Reports, 2022
We present the first reported case of a 68-year-old woman with an adrenal metastasis from a small cell carcinoma arising in an ovarian teratoma. The patient initially presented with an adrenal small cell carcinoma that was postulated to be a metastasis ...
Dallas Hampton   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Coexistent Non–Small Cell Carcinoma and Small Cell Carcinoma in a Patient Presenting with Hyponatremia

open access: yesCase Reports in Pulmonology, 2018
Despite recent advances in screening methods, lung cancer remains the leading cause of cancer-related deaths worldwide. By the time lung cancer becomes symptomatic and patients seek treatment, it is often too advanced for curative measures.
Mitchell D. Ross   +6 more
doaj   +1 more source

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