Results 91 to 100 of about 5,409,040 (244)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment
BiomedicinesUrothelial carcinoma (UC), also known as transitional cell carcinoma (TCC), is the second most frequently diagnosed urological tumor worldwide, and typically involves the bladder [...]
Ioannis Zachos
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
CHARACTERISTICS OF TRANSITIONAL CELL CARCINOMA OF THE BLADDER IN YOUNG ADULTS
Urology Research and Practice, 2019 Introduction: The incidence of transitional cell carcinoma of the bladder is increasing especially in all industrialized countries and an augmented number of young patients are encountered.
H. Cem IRKILATA +5 more
doaj +2 more sources
Squamous cell carcinoma antigen in genitourinary tumors
The International Journal of Biological Markers, 1989 We have evaluated the serum levels of squamous cell carcinoma (SCC) antigen in patients with adenocarcinoma of the kidney, adenocarcinoma of the prostate, germ cell tumors of the testis, transitional cell carcinoma of the bladder, and SCC of the penis ...
K.I. Wishnow +2 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Assesment of angiogenesis in basal cell carcinoma using CD31 &CD34 markers and relation with tumor invasiveness in histology [PDF]
Background & Objective : Tumor angiogenesis is essential for tumor growth and appears to play an importating role both in invasive growth and metastasis.
صفايی, زهرا +3 more
core
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
NON-TRANSITIONAL CELL CARCINOMA OF THE BLADDER
Urology Research and Practice, 2019 Introduction: Transitional cell carcinoma is the most common histopathologic type of bladder tumors. But bladder cancer is a heterogenous disease with an unpredictable clinical course.
Bülent GÜNLÜSOY +5 more
doaj +2 more sources