Results 131 to 140 of about 5,409,040 (244)

A collision of two primary renal neoplasms: A rare case report. [PDF]

Urol Case Rep
Chaker K, Khadhar A, Mosbahi B, Limem A, Ammous A, Nouira Y.   +5 more
europepmc   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

Synchronous renal cell carcinoma and transitional cell carcinoma of the bladder: A case report

, 2016
Synchronous multiple primary neoplasia is an uncommon occurrence. It should be kept in mind that there can be a second malignancy in patients with primary tumor in an organ of the genitourinary system.
KAYIGİL, ÖNDER, Okulu, Emrah, Akdemir, Fatih, Kiliç Yazgan, Aylin   +3 more
core  

Skin Basal Cell Carcinosarcoma in a Trichoblastic Guise-Molecular Characterization of a Novel Entity Mimicking a Pyoderma Gangrenosum. [PDF]

Dermatopathology (Basel)
Georg P, Blum R, Hunger R, Dislich B, Wolf R.   +4 more
europepmc   +1 more source

Rewiring Pyroptosis to Potentiate Cancer Immunotherapy via a Gasdermin D Agonist Bypassing Caspase‐3

Advanced Science, EarlyView.
This work introduces a small‐molecule agonist, DIBDO, that bypasses Casp‐3 to directly trigger GSDMD‐mediated pyroptosis in tumors. Activated by glutathione, DIBDO generates singlet oxygen and molecular iodine, blocking Casp‐3 pathways and inducing immunogenic cell death.
Dan Zhao, Lingling Zhang, Yue Wen, Lianghui Cheng, Sidan Tian, Fanling Meng, Liang Luo   +6 more
wiley   +1 more source

Walthard Cell Nests on the Serosal Surface of the Small Intestine Mimicking Metastatic Carcinoma: A Report of a First Case. [PDF]

Cureus
Albrahim MN, Arora R, Sultan A.
europepmc   +1 more source

A Supramolecular Thermal Switch for Precision Pyroptosis via Host−Guest Recognition and Electrostatic Interactions

Advanced Science, EarlyView.
A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu, Jie Zhou, Yibin Cao, Kunmin Ping, Borui Zhao, Yanrong Yang, Chunyang Yu, Xinyang Yu, Shaolong Qi   +8 more
wiley   +1 more source

Uncommon Presentation of a Benign Brenner Tumor Mimicking Malignancy: A Case Report. [PDF]

Case Rep Obstet Gynecol
Susilo SA, Harsono AB, Usman HA.
europepmc   +1 more source

Spatiotemporally Ultrasound‐Controlled Nanoparticles Reprogramming Immunostimulatory Antigen‐Presenting Cancer‐Associated Fibroblasts to Enhance Cancer Immunotherapy

Advanced Science, EarlyView.
We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai, Weikai Sun, Yuxuan Zhao, Daqian Sun, Ting Meng, Yafei Qi, Fengyang Jiang, Jintang Sun, Zhiliang Gao, Dexin Yu   +9 more
wiley   +1 more source

Malignant priapism as the presenting manifestation of penile metastasis following radical cystoprostatectomy for bladder urothelial carcinoma: a case report. [PDF]

J Surg Case Rep
Nayeri RK, Banouei F.
europepmc   +1 more source