Results 161 to 170 of about 72,739 (306)

Contrast-enhanced ultrasound in the diagnosis of neoplastic lesions of the urinary bladder. [PDF]

Cent European J Urol
Kufel J, Mitręga A, Magiera M, Bielówka M.   +3 more
europepmc   +1 more source

Penile Detumescence [PDF]

, 1991
Aboseif, Sherif R., Bosch, Ruud J. L. H., Bénard, Francois, Lue, Tom F., Stief, Christian Georg, Tanagho, Emil A.   +5 more
core  

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

A Rare Case of Collision Tumor at the Periampullary Region. [PDF]

Case Rep Pathol
Kale K, Chaudhari V, Ostwal V, Shrikhande SV, Deodhar K.   +4 more
europepmc   +1 more source

FASLG Derived from Fibroblasts in Hydroxyapatite‐Rich Microenvironment Induces Urothelial Anoikis to Trigger Randall's Plaque Exposure

Advanced Science, EarlyView.
Randall's plaques (RP) serve as the nidus for calcium oxalate (CaOx) kidney stones. The current study reveals that hydroxyapatite (HAP) crystals activate the THY1–GSK3α/β–β‐catenin axis in renal interstitial fibroblasts (hRIFs), inducing FASLG secretion.
Minghui Liu, Maolan Wu, Meng Gao, Yongchao Li, Miao Yuan, Zhangcheng Liao, Zhi Liu, Yizhou Wang, Yu Cui, Jinbo Chen, Cheng He, Zhiyong Chen, Feng Zeng, Hequn Chen, Zewu Zhu   +14 more
wiley   +1 more source

High Burden of Incidental and High-Grade Prostatic Carcinoma in Transurethral Resection of the Prostate (TURP) Specimens: A Retrospective Histopathological Analysis From Central India. [PDF]

Cureus
Jayant S, Yadav A, Ramchandani A, Gupta P, Hora MS, Gupta M, Nema MGS.   +6 more
europepmc   +1 more source

In Vivo CRISPR Screening Identifies the Glutamate Receptor GRIA2 as Promoting Peritoneal Metastasis of Gastric Cancer via Calcium‐Dependent β‐Catenin Activation

Advanced Science, EarlyView.
We identified GRIA2 as a critical driver of gastric cancer peritoneal metastasis through in vivo CRISPR screening. Mechanistically, GRIA2‐mediated calcium influx inhibits GSK3β and activates Wnt/β‐catenin signaling, driven by glutamate from cancer‐associated fibroblasts.
Jie Sun, Xu Yang, Wenchao Jiang, Chengbo Ji, Yingying Wu, Haoyu Sun, Xinyou Liu, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Junjie Zhao, Yuanyuan Ruan, Haojie Li, Xuefei Wang   +13 more
wiley   +1 more source

Adolescent Renal Tumours: Diagnostic and Therapeutic Challenges in a Transitional Age Group-A Multidisciplinary Case Report Series from a Single Center. [PDF]

Oncol Res
Ruggiero A, Fuccillo F, Di Paola V, Romano A, Maurizi P, Talloa D, Foschi N, Russo P, Racioppi M, Mastrangelo S, Attinà G.   +10 more
europepmc   +1 more source

Spongiosolysis [PDF]

, 1987
Gilbert, P., Stief, Christian Georg
core   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source