Results 31 to 40 of about 5,409,040 (244)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Snps of Gstm1, T1, P1, Epoxide Hydrolase and DNA Repair Enzyme Xrcc1 and Risk of Urinary Transitional Cell Carcinoma in Southwestern Taiwan

, 2009
A hospital-based case-control study was conducted near a former black- foot disease (BFD)-endemic area in southwestern Taiwan to examine the possible risk factors and genetic susceptibility for urinary transitional cell carcinoma (TCC) .
許鈴宜;邱文祥;黃冠華;陳祈玲;王淵宏;謝芳宜;陳建仁, HSU, LING-I;CHIU, ALLEN WEN-HSIANG;HUAN, STEVEN KUAN-HUA;CHEN, CHI-LING;WANG, YUAN- HUNG;HSIEH, FANG-I;CHEN, CHIEN-JEN   +1 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Transitional Cell Carcinoma of the Ovary

Taiwanese Journal of Obstetrics & Gynecology, 2006
Objective: Transitional cell carcinoma (TCC) of the ovary is a rare, recently recognized, subtype of ovarian surface epithelial cancer. We present a case of TCC of the ovary, managed by staging operation and followed by postoperative chemotherapy with ...
Chia-Hui Lin, Fu-Shing Liu, Esther Shih-Chu Ho   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Malignant Brenner tumor: Two case reports

Case Reports in Women's Health, 2018
Malignant Brenner tumor (MBT) is a rare ovarian tumor that, given the infrequency of the disease, has not been well documented in the literature. Diagnosing MBT both radiographically and histologically remains a challenge.
Luke King, Radhika P. Gogoi, Christopher Hummel, Ashlee Smith   +3 more
doaj   +1 more source

Metástasis cutánea de carcinoma de células de transición

Galicia Clínica, 2021
Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from transitional cell bladder carcinoma. Cutaneous metastases from primary genitourinary malignancies are rare and very few cases of skin metastasis from urothelial ...
Virginia Visconti, Adriana Soares
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Carrier cell-mediated cell lysis of squamous cell carcinoma by squamous cell carcinoma antigen 1 promoter-driven oncolytic adenovirus [PDF]

, 2009
The squamous cell carcinoma antigen (SCCA) serves as a serological marker for squamous cell carcinomas. Molecular cloning of the SCCA genomic region has revealed the presence of two tandemly arrayed genes, SCCA1 and SCCA2.
Yoshiyuki Koyama, Hiroyuki Hamakawa, Hiroshi Ito, Kenzaburo Tani, Junzo Desaki, Ting Zhang, Katsuyuki Hamada, Koh-ichi Nakashiro   +7 more
core  

The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004. [PDF]

, 2009
BACKGROUND: Extrapulmonary small cell carcinoma (EPSCC) is a rare cancer and few studies describe its epidemiology. Our objectives were to compare the incidence and survival of EPSCC in South East England with small cell carcinoma of the lung (SCLC), to ...
Jack, Ruth H, Jack Ruth H, Elizabeth A Davies, Jack, Ruth H., Wong Yien, Davies, Elizabeth A.; id_orcid, Henrik Møller, Mak, Vivian, Møller Henrik, Vivian Mak, Wong, Yien Ning S., Mak Vivian, Henrik, Moller; id_orcid, Yien Ning S Wong, Ruth H Jack, Davies Elizabeth A, Henrik, Møller, Davies, Elizabeth A, Wong, Yien Ning S   +18 more
core   +2 more sources