Results 31 to 40 of about 72,739 (306)

Transitional cell carcinoma of the endometrium and endometrial carcinoma with transitional cell differentiation [PDF]

Cancer, 1997
Transitional cell carcinoma (TCC) is rare in the female genital tract. Although it is most common in the ovary, small series of cases in the cervix have been reported, with isolated cases described in the fallopian tube, adnexa uteri, and endometrium.Eight cases of primary TCC involving the endometrium and 1 case of ovarian TCC metastatic to the ...
R A, Lininger, R, Ashfaq, J, Albores-Saavedra, F A, Tavassoli   +3 more
openaire   +2 more sources

Fos co-operation with PTEN loss elicits keratoacanthoma not carcinoma due to p53/p21^WAF-induced differentiation triggered by GSK3b inactivation and reduced AKT activity [PDF]

, 2008
To investigate gene synergism in multistage skin carcinogenesis, the RU486-inducible cre/lox system was employed to ablate PTEN function [K14.cre/D5PTENflx] in mouse epidermis expressing activated v-fos [HK1.fos].
Alexander, C.L., Chan, W-C., Greenhalgh, D.A., Quinn, J., Wu, H., Yao, D.   +5 more
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

Metastatic renal cell carcinoma masquerading as a primary ovarian mass in a post-operative case of meningioma and renal cell carcinoma

Rare Tumors, 2015
The clinical presentation of metastatic renal cell carcinoma to ovary is extremely rare as well as confusing due to its close resemblance to primary ovarian tumors, especially clear cell carcinoma.
Sangita Bohara, Biswajit Dey, Swapnil Agarwal, Jyotsna Naresh Bharti, Nita Khurana, Poonam Sachdeva   +5 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Chromosomal aberrations in transitional cell carcinoma that are predictive of disease outcome are independent of polyploidy [PDF]

, 1999
Objective To determine whether aneusomy for chromosomes 7, 9 and 17 (reported to predict recurrence in up to 65% of patients with superficial transitional cell bladder cancer and thus providing the opportunity for early and effective treatment) reflects ...
Adie, L., Bartlett, J.M.S., Going, J.J., Grigor, K.M., Watters, A.D.   +4 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Malignant Brenner tumor: Two case reports

Case Reports in Women's Health, 2018
Malignant Brenner tumor (MBT) is a rare ovarian tumor that, given the infrequency of the disease, has not been well documented in the literature. Diagnosing MBT both radiographically and histologically remains a challenge.
Luke King, Radhika P. Gogoi, Christopher Hummel, Ashlee Smith   +3 more
doaj   +1 more source

A taxonomy of epithelial human cancer and their metastases [PDF]

, 2009
Background: Microarray technology has allowed to molecularly characterize many different cancer sites. This technology has the potential to individualize therapy and to discover new drug targets.
Olivier Gevaert, Anneleen Daemen, Bart De Moor, Louis Libbrecht, CH Chung, TR Golub, B Weigelt, T Sorlie, DN Hayes, CM Perou, A Bhattacharjee, A Alizadeh, T Sorlie, S Ramaswamy, TJ Giordano, D Rhodes, S Ramaswamy, GV Glinsky, N Pavlidis, RW Tothill, RA Bender, G Bloom, XJ Ma, D Talantov, CL Wilson, M Dai, A Subramanian, G Dennis, DW Huang, PS Nelson, M Cuatrecasas, JH Eichhorn, SK Tickoo, G Ayala, J Brugarolas, P Staller, X Liu, BJ Yoder, M Lacroix, B Weigelt, C Sotiriou, EA Rakha, C Sotiriou, AV Ivshina, M Ignatiadis, JX Yu, Z Hu, EK Sloan, AK Witkiewicz, L Lukes, AK Witkiewicz, XJ Ma, K Pavlakis, S Troup, K Wennmalm, P Schedin, G Finak, KA Oien, HG Laberke, MB Amin, SJ Jung, RC Bast Jr, JD Seidman, H Kang, H Naora, SM Smorenburg, T Sukata, IJ Matouk, S Khambata-Ford, MA Pantaleo, DH Ki, A Ramasamy, M Snyder, J Belmont, K Chin, LD Miller, J Pittman   +76 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source