Results 1 to 10 of about 59,191,543 (142)
British Journal of Pharmacology, Volume 178, Issue 11, Page 2284-2304, June 2021., 2021 Background and Purpose Inflammation associated with the tumour microenvironment (TME) is critical for cancer development, and immunotherapeutic strategies modulating the immune response in cancer have been crucial. In this study, a methotrexate‐loaded (MTX) poly(lactic‐co‐glycolic acid)‐based (PLGA) drug nanocarrier covered with polyethyleneimine (Pei)
Rômulo S. Cavalcante +7 more
wiley +1 more source
miR‐367 as a therapeutic target in stem‐like cells from embryonal central nervous system tumors
Molecular Oncology, Volume 13, Issue 12, Page 2574-2587, December 2019., 2019 Aberrant expression of OCT4A and miR‐367 regulates stem‐like aggressive traits in embryonal central nervous system (CNS) tumor cells. We show that miR‐367 is carried by microvesicles derived from OCT4A‐overexpressing tumor cells, miR‐367 silencing reduces aggressive tumor traits, and treatment with miR‐367 inhibitor improves survival of tumor‐bearing ...
Carolini Kaid +5 more
wiley +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2019, Issue 1, 2019., 2019 Breast cancer is the leading cause of cancer‐associated death among women worldwide. Its high mortality rate is related to resistance towards chemotherapies, which is one of the major challenges of breast cancer research. In this study, we used label‐free mass spectrometry‐ (MS‐) based proteomics to investigate the differences between circulating ...
Bruno R. B. Pires +8 more
wiley +1 more source
Combined Effects of Pericytes in the Tumor Microenvironment
Stem Cells International, Volume 2015, Issue 1, 2015., 2015 Pericytes are multipotent perivascular cells whose involvement in vasculature development is well established. Evidences in the literature also suggest that pericytes display immune properties and that these cells may serve as an in vivo reservoir of stem cells, contributing to the regeneration of diverse tissues.
Aline Lopes Ribeiro +2 more
wiley +1 more source
Case Reports in Urology, Volume 2012, Issue 1, 2012., 2012 Hypernephroma can present as a variety of paraneoplastic, nonmetastatic conditions, including vasculitis, and rarely a lupus‐type anticoagulant. Nephrectomy leads to the resolution of the systemic complaints. Malignancy, in this case hypernephroma, can present as an immune‐mediated paraneoplastic syndrome which resolves after removal of the underlying ...
Nigel P. Murray +6 more
wiley +1 more source
Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis
Advanced Materials, Volume 36, Issue 34, August 22, 2024.Natural hydrogels derived from decellularized porcine or human kidney tissues are used to generate kidney organoids from human pluripotent stem cells, resulting in the enrichment of organoids’ endogenous vascular component and improved renal differentiation. Exploiting the autonomous capacity of kidney organoids to exhibit endogenous vascularization in
Elena Garreta +18 more
wiley +1 more source
23rd Congress of the European Hematology Association Stockholm, Sweden, June 14‐17, 2018
, 2018 HemaSphere, Volume 2, Issue S1, Page 1-1113, June 2018.
wiley +1 more source
Annual Sickle Cell & Thalassaemia Conference (ASCAT) ‐ October 2023
HemaSphere, Volume 8, Issue S3, December 2024.
wiley +1 more source
Tongue squamous cell carcinoma and bilateral kidney metastases [PDF]
Rev Fac Cien Med Univ Nac Cordoba, 2021 Bruballa R +3 more
europepmc +1 more source
[Syndrome of Stauffer: A lethal stranger]. [PDF]
Aten Primaria, 2022 Casal Álvarez J +2 more
europepmc +1 more source