Results 11 to 20 of about 8,659 (227)

Frequent apocrine changes in pleomorphic adenoma with malignant transformation: a possible pre-malignant step in ductal carcinoma ex pleomorphic adenoma [PDF]

Journal of Pathology and Translational Medicine, 2023
Background The most common type of carcinoma ex pleomorphic adenoma (CPA) is histologically equivalent to salivary duct carcinoma, which has an apocrine phenotype.
Joon Seon Song, Yeseul Kim, Yoon-Se Lee, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim, Kyung-Ja Cho   +6 more
doaj   +3 more sources

A Rare De Novo Myoepithelial Carcinoma Ex Pleomorphic Adenoma in a Young Woman [PDF]

Case Reports in Otolaryngology, 2020
Carcinoma ex pleomorphic adenoma, an uncommon neoplasm of the parotid gland, accounts for less than 4% of salivary gland tumors. It arises from a benign pleomorphic adenoma presenting in the sixth to eighth decades of life.
Geeta Ahuja, Delaram J. Taghipour, Olubode A. Olufajo, Bonnie C. Davis, Babak Shokrani, William R. Bond   +5 more
doaj   +4 more sources

Carcinoma ex Pleomorphic Adenoma: Multi-Institutional Retrospective Cohort Study. [PDF]

OTO Open
Objective Carcinoma ex pleomorphic adenoma (CXPA) is a rare malignancy and survival rates vary throughout literature. The primary objectives are to study overall survival (OS), disease‐specific survival (DSS), locoregional recurrence‐free survival (LRFS),
Kassalow B, Prince A, Bullock M, Neal MH, Hart R, Afif AA, Forner D.   +6 more
europepmc   +3 more sources

Complete Response in Salivary Duct Carcinoma Ex Pleomorphic Adenoma With Upfront Combination of Trastuzumab and Chemo-Hormonal Therapy. [PDF]

Cureus
Salivary duct carcinoma (SDC) is one of the rarest malignancies. It can arise de novo or from pre-existing pleomorphic adenoma (carcinoma ex pleomorphic adenoma - CXPA) and can be very aggressive. Here, we present one such case of a 48-year-old male with
Gupta A, Lakshmi Narayanan A, Kashyap V, Gupta S.   +3 more
europepmc   +3 more sources

Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland with Intracranial Extension. [PDF]

J Neurol Surg Rep
Carcinoma ex-pleomorphic adenoma (CXPA) of the lacrimal gland is rare, and its management can be complex given its anatomic location. In this case report, we describe our approach to multidisciplinary management of a CXPA with intracranial extension.
Sharbel D, Atekha O, Rahimi S, Byrd JK.
europepmc   +3 more sources

A rare case of epithelial-myoepithelial carcinoma ex pleomorphic adenoma of the parotid gland: Radiologic-pathologic correlation [PDF]

Radiology Case Reports, 2023
Carcinoma ex pleomorphic adenoma is a carcinoma that arises from a primary or recurrent benign pleomorphic adenoma. The prevalence of epithelial-myoepithelial carcinoma is low, and this histological type accounting for only 1% of all salivary gland ...
Chika Yamada, MD, Akira Baba, MD, PhD, Hideomi Yamauchi, MD, PhD, Nobuhiro Ogino, MD, PhD, Masato Nagaoka, MD, Ai Iwauchi, MD, Miku Maeda, MD, Nei Fukasawa, MD, Masayuki Shimoda, MD, PhD, Taisuke Mori, MD, PhD, Hiroya Ojiri, MD, PhD   +10 more
doaj   +2 more sources

Carcinoma Ex Pleomorphic Adenoma [PDF]

Pathology, 2014
The development of malignancy from a pleomorphic adenoma is well recognised but is considerably more complex than previously thought. Apart from tumours with obvious histological malignancy, there are some pleomorphic adenomas that have atypical histological features only and yet others with malignant biological behaviour but with benign histology, the
Alena Skálová, Henrik Hellquist
core   +6 more sources

Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Submandibular Gland: A Case Report. [PDF]

Cureus, 2023
Carcinoma ex pleomorphic adenoma (Ca-ex-PA) is a rare tumor that arises from the malignant transformation of a primary or recurrent pleomorphic adenoma. Despite being benign, pleomorphic adenomas can rarely undergo malignant transformation.
Syrnioti G, Syrnioti A, Abdullah A, Lui X, Mendoza E.   +4 more
europepmc   +2 more sources

Extracellular matrix remodelling and stiffening contributes to tumorigenesis of salivary carcinoma ex pleomorphic adenoma--A study based on patient-derived organoids. [PDF]

Cell Biosci, 2023
Background Salivary carcinoma ex pleomorphic adenoma (CXPA) is defined as a carcinoma that develops from benign pleomorphic adenoma (PA). Abnormally activated Androgen signaling pathway and amplification of HER-2/ neu(ERBB-2) gene are known to be ...
Chen W, Gu T, Chen Q, Qu C, Zhang C, Hu Y, Xia R, Zhang Y, Wang M, Huang X, Li J, Shi C, Tian Z.   +12 more
europepmc   +2 more sources

Medium-sized buccal mucosa defect reconstruction with buccal advancement flap in mucoepidermoid carcinoma ex pleomorphic adenoma: a case report. [PDF]

Ann Med Surg (Lond), 2023
Introduction and importance: Mucoepidermoid carcinoma (MEC) ex pleomorphic adenoma is a rare type of salivary gland cancer. Surgical resection remains the standard therapy for this malignancy.
Srivanitchapoom C, Yata K.
europepmc   +2 more sources