BRCA1/2 mutations in salivary pleomorphic adenoma and carcinoma-ex-pleomorphic adenoma [PDF]
It is hypothesized that carcinoma-ex-pleomorphic adenoma (Ca-ex-PA) is malignant from the beginning or is a malignant transformation of a recurrent or a long-standing pleomorphic adenoma (PA). The accumulation of genetic instabilities is suggested to be the main reason for malignant transformation in PA.
Irani, Soussan +1 more
openaire +4 more sources
Lacrimal gland tumors in Turkey: types, frequency, and outcomes. [PDF]
AIM: To evaluate the clinical, radiological, and treatment features of lacrimal gland tumors. METHODS: Retrospective review of 99 eyes of 92 patients with lacrimal gland tumors diagnosed and managed in a single institution between January 1999 and March ...
Erden, Esra +3 more
core +2 more sources
Analysis of the clinical relevance of histological classification of benign epithelial salivary gland tumours [PDF]
IntroductionA vast increase in knowledge of numerous aspects of malignant salivary gland tumours has emerged during the last decade and, forseveral reasons, thishas not been the case in benign epithelial salivary gland tumours.
Andreasen, Simon +10 more
core +4 more sources
TP53 and p16INK4A, but not H-KI-Ras, are involved in tumorigenesis and progression of pleomorphic adenomas. [PDF]
The putative role of TP53 and p16INK4A tumor suppressor genes and Ras oncogenes in the development and progression of salivary gland neoplasias was studied in 28 cases of pleomorphic adenomas (PA), 4 cases of cystic adenocarcinomas, and 1 case of ...
AGNESE, Valentina +18 more
core +1 more source
Malignant transformation of salivary gland pleomorphic adenoma: proof of principle
Supposed risk of malignant transformation of salivary gland pleomorphic adenoma (SGPA) is an important reason for aggressive retreatment in recurrent pleomorphic adenoma (RPA).
Matthijs H Valstar +8 more
doaj +1 more source
Neoplasms of the salivary glands in a Turkish adult population [PDF]
Objective: This retrospective study aimed to investigate the types and distribution of neoplasm of salivary glands in a Turkish population. Study Design: The histological diagnosis records of the Department of Pathology at Cumhuriyet University were ...
Elagoz, Sahende +5 more
core +1 more source
Tuberculosis (TB) and malignancy are two lethal diseases that cause significant morbidity and mortality in developing countries like India. Extrapulmonary tuberculosis (TB) constitutes about 15 to 20 per cent of all cases of tuberculosis with lymph nodes
Manjari Shah
doaj +1 more source
Differential expression of topoisomerase IIα protein in salivary gland carcinomas: histogenetic and prognostic implications [PDF]
BACKGROUND: Salivary gland carcinomas are relatively uncommon heterogeneous malignancies characterized by locoregional invasion and distant metastasis.
Hideichi Shinkawa +6 more
core +2 more sources
Carcinoma ex pleomorphic adenoma of the parotid gland with cardiac metastasis
Pleomorphic adenomas are the most common neoplasms of the major salivary glands. They are also known as benign mixed tumors because of the presence of both epithelial and mesenchymal elements.
Anuja Bhandari +2 more
doaj +1 more source
Three Cases of Noninvasive Carcinoma ex Pleomorphic Adenoma of the Parotid Gland and a Literature Survey Focusing on their Clinicopathologic Features [PDF]
Only 30 cases of non-invasive carcinoma ex pleomorphic adenoma have been reported in the English language literature. Here, we report on three cases of non-invasive carcinoma ex pleomorphic adenoma.
ARIMA Syuei +7 more
core +2 more sources

