Results 231 to 240 of about 2,761,482 (311)

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Breast cancer in association with lobular carcinoma in situ

, 1985
Neville C. Davis, Robert Baird
openalex   +1 more source

Harnessing Jasminum Bioactive Compounds: Updated Insights for Therapeutic and Food Preservation Innovations

Food Frontiers, EarlyView.
Jasminum bioactives improve food preservation by providing antimicrobial and antioxidant effects, especially when incorporated into active packaging, edible films, and nanoformulations that enhance stability and controlled release. They also offer many pharmacological benefits, including anti‐inflammatory, neuroprotective, and wound‐healing properties.
Antonio Rescigno, Paolo Zucca, Stefania Peddio, Sriranjani Srikanth, Niharika Prakash Kaushik, Nanjangud Venkatesh Anil Kumar, Gerardo Leyva‐Gómez, Dorota Kregiel, Ibrahim M. Abu‐Reidah, Surjit Sen, Krishnendu Acharya, William N. Setzer, Marta Palma‐Morales, Miquel Martorell, Daniela Calina, Celia Rodríguez‐Pérez, Javad Sharifi‐Rad, William C. Cho   +17 more
wiley   +1 more source

Surgical Approaches to Pre‐Auricular Cutaneous Squamous Cell Carcinomas Extending to the Temporal Bone

Head &Neck, EarlyView.
ABSTRACT Background Standardized surgical approaches to advanced pre‐auricular cutaneous squamous cell carcinomas (cSCC) are lacking. Methods Fifty–four patients who underwent lateral temporal bone resection (LTBR) for pre‐auricular cSCC were grouped into “Levels” of increasing disease spread.
Michael Schachtel, Mitesh Gandhi, James Bowman, Mark Midwinter, Benedict Panizza   +4 more
wiley   +1 more source

Oncogenic Human Papillomaviruses Drive One‐Third of Sinonasal Squamous Cell Carcinoma and Are Not Mutually Exclusive for Gene Mutations

Head &Neck, EarlyView.
ABSTRACT Background The detection rate of oncogenic human papillomaviruses (HPVs) in sinonasal squamous cell carcinomas (SNSCCs) varies among studies. The mutational landscape of SNSCCs remains poorly investigated. Methods We investigated the prevalence and prognostic significance of HPV infections based on p16 protein expression, HPV‐DNA detection ...
Maxime Henrion, Valérie Costes‐Martineau, Ignacio González Bravo, Nathalie Boulle, Jérôme Solassol, Julie Vendrell, Renaud Garrel, Aude Trinquet, Vanessa Lacheretz‐Szablewski   +8 more
wiley   +1 more source

Use of intravesical valrubicin in clinical practice for treatment of nonmuscle-invasive bladder cancer, including carcinoma in situ of the bladder

Therapeutic Advances in Urology, 2014
Michael Cookson, Sam S. Chang, C. Lihou, Thomas Li, Samira Q Harper, Z. Lang, R. Tutrone   +6 more
semanticscholar   +1 more source

Identification of type I collagen-producing cells in human gastrointestinal carcinomas by non-radioactive in situ hybridization and immunoelectron microscopy.

, 1992
Haruo Ohtani, Atsushi Kuroiwa, Masuo Obinata, Akira Ooshima, H Nagura   +4 more
openalex   +1 more source

In situ labeling of nuclear DNA fragmentation in normal oral epithelia and squamous cell carcinomas.

, 1994
Yoshihiro Abiko, Tomoyuki Ohuchi, Hisomu Nakahata, Toshiyuki Sadaoka, Masami Kanda, Tohru Kaku   +5 more
openalex   +2 more sources

Influence of a nationwide colorectal cancer screening program on the incidence of synchronous colorectal peritoneal metastases

International Journal of Cancer, EarlyView.
What's New? Colorectal cancer screening has been shown to decrease the incidence of the disease and allow detection at an earlier stage. Here, the authors also show that, since the introduction of the colorectal cancer screening program in the Netherlands in 2014, the incidence of synchronous peritoneal metastases in colorectal cancer patients has ...
Laskarina J. K. Galanos, Anouk Rijken, Marloes A. G. Elferink, Niels F. M. Kok, Felice N. van Erning, Ignace H. J. T. De Hingh   +5 more
wiley   +1 more source

Application of microwave(MW)-fixed tissue samples to in situ hybridization: Detection of carcinoembryonic antigen(CEA) mRNA and oncogene transcripts in MW-fixed colorectal carcinomas using sulfonated probes.

, 1990
Masahiko Murotani, Hideki Morimoto, Takushi Monden, Masahiko Higashiyama, Y. Kawasaki, Takashi Shimano, Takesada Mori   +6 more
openalex   +2 more sources