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Delivery of Human iPSC‐Derived RPE Cells in Healthy Minipig Retina Results in Interaction Between Photoreceptors and Transplanted Cells [PDF]

open access: yesAdvanced Science, Volume 12, Issue 20, May 29, 2025.
Human induced pluripotent stem cell‐derived retinal pigment epithelial (hiPSC‐RPE) cells, cultured on a clinically relevant PDLLA scaffold, are transplanted into immunosuppressed minipigs. The study demonstrates the viability, integration, and preservation of RPE‐specific features without gliosis or neuroinflammation, supporting their potential as a ...
Anna Macečková Brymová   +27 more
wiley   +2 more sources

el escultor ernesto cardenal [PDF]

open access: yesPolis, 2007
The author offers an analysis of the sculptoric work of whom we know mostly as a poet, Ernesto Cardenal, presenting him as a representative sculptor, who has developed the subjects of religiosity, animal and plant’s kingdoms, allowing in his work a confluence between primitive culture and modern art.
openaire   +2 more sources

Dravet syndrome: From neurodevelopmental to neurodegenerative disease?

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy caused by SCN1A haploinsufficiency in the majority of cases. Caregivers of adults with DS often complain about the loss of previously acquired skills. We set out to explore these perceptions and determine whether abnormalities reported were detectable in ...
Arunan Selvarajah   +39 more
wiley   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Money Talks? The Effectiveness of Sanctions in the ‘Rule of Law’ Conflict in the European Union

open access: yesJCMS: Journal of Common Market Studies, EarlyView.
Abstract The European Union (EU) responded to democratic backsliding in Hungary and Poland by implementing a sanctions toolbox, which includes the Article 7 Treaty on European Union (TEU) mechanism, infringement procedures and funding conditionality.
Adam Holesch, Clara Portela
wiley   +1 more source

Association of Skeletal Facial Pattern With Treatment Response of Obstructive Sleep Apnoea Using Mandibular Advancement Devices – A Cluster Analysis

open access: yesJournal of Oral Rehabilitation, EarlyView.
xxx ABSTRACT Background Mandibular advancement devices (MADs) are an effective treatment for obstructive sleep apnoea (OSA), though individual responses to therapy can vary. Objectives This study aims to: (1) examine how craniofacial characteristics are associated with MAD effectiveness to refine patient selection and improve outcomes; and (2) assess ...
Sara Camañes‐Gonzalvo   +6 more
wiley   +1 more source

Current perspective on dental black stain of bacterial origin: A narrative review

open access: yesEuropean Journal of Oral Sciences, Volume 133, Issue 3, June 2025.
Abstract Dental black stain is a form of external discoloration appearing as a dark line or an incomplete coalescence of dark spots in the cervical third of the tooth. This review aims to provide an up‐to‐date clinical and biological summary of dental black stain of bacterial origin.
Ahmed Al‐Shareef   +5 more
wiley   +1 more source

Individualised Therapy for Obstructive Sleep Apnoea: Predictive Models and Anatomical Phenotyping of Mandibular Advancement Devices Responses

open access: yesOrthodontics &Craniofacial Research, Volume 28, Issue 3, Page 485-495, June 2025.
ABSTRACT Objectives This non‐randomised clinical study aimed to identify the phenotypic characteristics that distinguish responders from non‐responders. Additionally, it sought to establish a predictive model for treatment response to obstructive sleep apnoea (OSA) using mandibular advancement devices (MAD), based on the analysed phenotypic ...
Sara Camañes‐Gonzalvo   +7 more
wiley   +1 more source

Predictive Model of Endodontic Access in Maxillary Central Incisors Using Cone Beam Computed Tomography

open access: yesEngineering Reports, Volume 7, Issue 5, May 2025.
This study develops a predictive model for endodontic access in maxillary central incisors using CBCT data. The model integrates anatomical and socio‐demographic variables to guide clinicians in optimizing access points, depths, and angles, improving accuracy, efficiency, and preserving tooth structure in root canal treatments.
Maria Llacer‐Martínez   +4 more
wiley   +1 more source

“Overdried, Without Curing? F*Ck, this [Is Supposed to be] Government Licensed Skunk!” Medical Cannabis and the Refracted Publics Within an Online Polish Drug Forum

open access: yesSociological Inquiry, Volume 95, Issue 2, Page 271-287, May 2025.
In this article, we analyze a Polish drug forum as a refracted public by focusing on the intersection of the digital space and illicit substances. To illuminate the reception of the medical cannabis industry in the social worlds of people who use cannabis, we apply qualitative thematic analysis of the content of the major Polish drug forum. The results
Michał Wanke   +2 more
wiley   +1 more source

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