Results 111 to 120 of about 18,197 (205)

Precision Cardio-Oncology and Nuclear Imaging: Current Applications, Molecular Innovations, and Future Trajectories. [PDF]

Cancers (Basel)
Ayalew BD, Haq MAU, Farooq T, Mubarika M, Umar M, Shafique U, Rehman A, Eladl HH, Toor AA, Fatima E, Sharew TM, Baig MMA, Smith DN, Addison D.   +13 more
europepmc   +1 more source

Remote‐Controlled Release of Nitric Oxide by Plasmonic Waveguide Coated With Metal–Organic Frameworks

Small, EarlyView.
Remote‐controlled intracellular delivery is achieved using a plasmonic waveguide coated with a photoresponsive NO‐releasing MOF. Surface plasmon polariton propagation remotely induces photocleavage and localized nitric oxide release in a target single live cell without direct light exposure, while biological relevance is demonstrated through transient ...
Tomoko Inose, Javier Lopez‐Cabrelles, Javier Troyano, Shun Tokuda, Elí Sánchez‐González, Nobuaki Takahashi, Yasuo Mori, Kenji Hirai, Hiroshi Uji‐i, Shuhei Furukawa   +9 more
wiley   +1 more source

A Spatio-Temporal Diffusion Model for Cardiac Real-Time Imaging. [PDF]

Magn Reson Med
Schad O, Heidenreich JF, Petri N, Hartung V, Kollmann A, Bley TA, Nordbeck P, Petritsch B, Wech T.   +8 more
europepmc   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Robustness of heart dose against cardiac cycle in breast cancer radiotherapy with deep inspiration breath-hold. [PDF]

Radiol Phys Technol
Yanagi Y, Monzen H, Aoki K, Harada N, Ohashi K, Hayashi M, Kosaka H, Iguchi H.   +7 more
europepmc   +1 more source

Endocardial obliterative left atrial appendage closure by inverted purse-string plication. [PDF]

JTCVS Tech
Nakamura Y, Nakayama T, Kuroda M, Yasumoto Y, Shirai C.   +4 more
europepmc   +1 more source

Geometry‐Related Technical Complications After LVAD Implantation: Impact on Device Dysfunction and Clinical Outcomes

Artificial Organs, EarlyView.
Preventable geometric failure modes, such as outflow graft kinking and inflow malposition, frequently cause HeartMate 3 dysfunction. This study identifies these complications as key drivers of device‐related morbidity, highlighting the importance of optimized surgical positioning to ensure long‐term device performance and improved clinical outcomes ...
Ali Saad Merzah, Ezin Deniz, Sara Knigge, Jasmin Hanke, Alina Zubarevich, Mohamad Dia, Chaikovska Sofia, Todurov Borys, Saeed Torabi, Bastian Schmack, Alexander Weymann, Zurab Darbaidze, Josephina Haunschild, Christian D. Etz, Max Biewer, Arjang Ruhparwar, Jan D. Schmitto, Günes Dogan   +17 more
wiley   +1 more source

Inhibition of late sodium current prevents pathological hyperactivation of calcium/calmodulin‐dependent protein kinase IIδ in a murine model of acute doxorubicin‐related cardiotoxicity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Doxorubicin (DOX) is a highly effective anthracycline, whose clinical application for cancer is limited by cardiotoxicity. The mechanisms underlying doxorubicin‐induced toxic cardiomyopathy (DICM) involve electrophysiological remodelling with intracellular Na+ overload because of increased late INa and hyperactivation of
Anna‐Lena Feder, Anna‐Maria Pfützenreuter, Lea Maria Funke, Maria Johanna Baier, Daniel Tarnowski, Laura Stengel, Lars Siegfried Maier, Can Martin Sag   +7 more
wiley   +1 more source

Robustness evaluation of carbon ion radiotherapy for ventricular tachycardia. [PDF]

Phys Imaging Radiat Oncol
Miyasaka Y, Ichikawa M, Souda H, Tominaga Y, Wakisaka Y, Chai H, Ishizawa M, Koto M, Iwai T.   +8 more
europepmc   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source