Results 101 to 110 of about 3,508,587 (362)

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

Rescue of Pressure Overload-Induced Heart Failure by Estrogen Therapy. [PDF]

open access: yes, 2016
BackgroundEstrogen pretreatment has been shown to attenuate the development of heart hypertrophy, but it is not known whether estrogen could also rescue heart failure (HF).
Bopassa, Jean C   +12 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

Cardiac Rehabilitation on Health Behaviors and Clinical Outcomes Among Myocardial Infarction Patients [PDF]

open access: yes, 2016
The lack of adherence to health behaviors in cardiac rehabilitation (CR) is the leading cause of recurrent myocardial infarction (MI) in Indonesia. This randomized control trial (RCT) study was conducted to examine the effect of a family based self ...
Herliani, Y. K. (Yusshy)   +2 more
core  

Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery [PDF]

open access: yes, 2020
Background Laboratory studies demonstrate glucose-insulin-potassium (GIK) as a potent cardioprotective intervention, but clinical trials have yielded mixed results, likely because of varying formulas and timing of GIK treatment and different clinical ...
Chen, Wensheng   +12 more
core   +1 more source

Real-time optical manipulation of cardiac conduction in intact hearts [PDF]

open access: yes, 2018
Optogenetics has provided new insights in cardiovascular research, leading to new methods for cardiac pacing, resynchronization therapy and cardioversion.
Bocchi, L.   +16 more
core   +2 more sources

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Transdiaphragmatic surgical access by thoracoscopy for epicardial pacemaker implantation in horses [PDF]

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia
Cardiac arrhythmias are common in horses and can lead to a decline in performance and sudden death. The use of cardiac pacemakers in horses has been poorly investigated, with a scarcity of description and development of techniques for the device ...
A.R.C. Gomes   +5 more
doaj   +1 more source

Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]

open access: yes, 2014
Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro   +5 more
core   +3 more sources

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