Results 131 to 140 of about 4,738,170 (353)
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source
Ischemic preconditioning at a remote site prevents acute kidney injury in patients following cardiac surgery [PDF]
Robert F. Zimmerman +6 more
openalex +1 more source
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
Macrophages promote both injury and repair after myocardial infarction, but discriminating functions within mixed populations remains challenging. Here we used fate mapping, parabiosis and single-cell transcriptomics to demonstrate that at steady state ...
Sarah A. Dick +20 more
semanticscholar +1 more source
Objective Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged ≥70 years old.
Amanda J. Rickard +15 more
wiley +1 more source
Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S. +2 more
core
Extracellular Matrix Secretion by Cardiac Fibroblasts [PDF]
Mélanie Abonnenc +16 more
openalex +1 more source
Objective Asymptomatic hyperuricemia is a precursor of gout and is also associated with cardiovascular disease and chronic kidney disease. The aim of this study was to understand perceptions about asymptomatic hyperuricemia and views about urate‐lowering therapy in people with asymptomatic hyperuricemia. Methods Participants in a multinational study of
Nicola Dalbeth +19 more
wiley +1 more source
A Multiphysics Biventricular Cardiac Model: Simulations With a Left-Ventricular Assist Device
Computational models have become essential in predicting medical device efficacy prior to clinical studies. To investigate the performance of a left-ventricular assist device (LVAD), a fully-coupled cardiac fluid-electromechanics finite element model was
Azam Ahmad Bakir +5 more
doaj +1 more source
Rabbit models of heart disease. [PDF]
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core
Rapamycin persistently improves cardiac function in aged, male and female mice, even following cessation of treatment [PDF]
Ellen Quarles +14 more
openalex +1 more source

