Results 61 to 70 of about 2,317,587 (307)

Cardiac Endocrine Function and Hormonal Interplay in Pediatrics: From Development to Clinical Implications

Biomedicines
The endocrine system plays a pivotal role in all stages of cardiac development and in maintaining the structural and functional integrity of the heart.
Valeria Calcaterra, Savina Mannarino, Filippo Puricelli, Giulia Fini, Giulia Cecconi, Martina Evangelista, Beatrice Baj, Cassandra Gazzola, Gianvincenzo Zuccotti   +8 more
doaj   +1 more source

Covid 19 and its cardiovascular effects

Annals of Cardiac Anaesthesia, 2020
COVID-19 pandemic is mainly related with the pulmonary problems initially but now as the pandemic is growing it is observed that almost all organ systems of the body are affected.
Amit Rastogi, Prabhat Tewari
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Protective Effect of Sumac and Terebinth Extracts Against the Negative Effects of Breast Cancer on Cardiac Tissues of in Rats

Revista Científica
Due to the toxic side effects of chemotherapeutic drugs used in breast cancer, interest in medicinal plants has increased in order to develop alternative cancer drugs.
Figen Erdem Erişir, Sevinç Aydın, Zeynep Tuzcu, Ökkeş Yılmaz   +3 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

The Effects of Overexpressing K2p Channels in Various Tissues on Physiology and Behaviors

Insects
Two-pore-domain K+ channels (K2p), known previously as leak channels, are responsible for maintaining the resting membrane potential of cells. Fifteen subtypes are known to exist in humans and eleven are known in Drosophila melanogaster, as well as six ...
Alaina C. Taul, Elizabeth R. Elliott, Douglas A. Harrison, Robin L. Cooper   +3 more
doaj   +1 more source

Innate Functions of Dendritic Cell Subsets in Cardiac Allograft Tolerance

Frontiers in Immunology, 2020
Survival rates after heart transplant have significantly improved over the last decade. Nevertheless, long-term allograft viability after 10 years remains poor and the sequelae of transplant-associated immunosuppression increases morbidity.
Samantha Schroth, Kristofor Glinton, Xunrong Luo, Edward B. Thorp, Edward B. Thorp   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Carbon based materials in conducting tissue engineering

Materials Research Express
Conducting materials based on carbon have been widely investigated in conducting tissue engineering applications due to their outstanding physical, chemical, thermal, and electric properties in recent years. Carbon based conductive materials can generate
Elif Sancar, Büşra Oktay, Esma Ahlatcıoğlu Özerol   +2 more
doaj   +1 more source

An overview on cardiac involvement in Inborn Errors of Metabolism: from clinical clues to nutritional management strategies

Frontiers in Cardiovascular Medicine
Inborn Errors of Metabolism (IEMs) account for a significant proportion of cardiomyopathies presenting with a wide spectrum of cardiac involvement, from isolated manifestations to multisystem syndromes.
Chiara Montanari, Chiara Montanari, Veronica Maria Tagi, Veronica Maria Tagi, Martina Tosi, Martina Tosi, Eliana Stucchi, Eleonora Maria Pisano, Irene Raso, Giulia Fini, Laura Fiori, Savina Mannarino, Gianvincenzo Zuccotti, Gianvincenzo Zuccotti, Elvira Verduci, Elvira Verduci   +15 more
doaj   +1 more source