Results 281 to 290 of about 396,911 (360)

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

Animal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong, Wei Qian, Deji Song, Kang Li, Li Zhang, Li Shi   +5 more
wiley   +1 more source

Race and Resuscitation: Evolving Trends in Survival After In-Hospital Cardiac Arrest. [PDF]

J Am Heart Assoc
Mohamed A, Andrea L, Gong MN, Naqvi A, Orsi D, Sherrod CF, Chan PS, Okubo M, Moskowitz A, American Heart Association’s Get With The Guidelines®‐Resuscitation Investigators *.   +9 more
europepmc   +1 more source

Wireless blood pressure sensor implantation in sheep: A detailed technique

Animal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer, Paul Ecker, Judith Radloff, Katharina Heissl, Smruti Mirchandani, Sabine Leitner, Bruno Mora, Martin Czerny, Roman Gottardi, Michael Moore, Bruno K. Podesser   +10 more
wiley   +1 more source

Are Thrombolytics Useful in Out-of-Hospital Cardiac Arrest? [PDF]

Cureus
Abou Dagher G, Alwan J, Bou Chebl R, Sarieddine A, Fakhreddine OY, Hatoum M, Bou Ammar D, Ghazzal Z.   +7 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Resuscitated Cardiac Arrest From Cardiac Sarcoidosis in a Professional Basketball Player: A Slam Dunk Diagnosis? [PDF]

JACC Case Rep
Pillai B, Hardin EA, Link MS, Kato K, Levine BD.   +4 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Lessons from the finish line: understanding cardiac arrest in endurance racing. [PDF]

Europace
Skjelbred T, Sharma S, Tfelt-Hansen J.
europepmc   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Attention performance in emergency physicians: the effect of shift duration and cardiac arrest cases. [PDF]

BMC Emerg Med
Yasak İH, Demir HA, Şeyhanlı ES, Giden R, Barut E.   +4 more
europepmc   +1 more source