Results 71 to 80 of about 1,925,495 (406)

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm.

New England Journal of Medicine, 2019
BACKGROUND Moderate therapeutic hypothermia is currently recommended to improve neurologic outcomes in adults with persistent coma after resuscitated out-of-hospital cardiac arrest.
J. Lascarrou, H. Merdji, A. Le Gouge, G. Colin, G. Grillet, P. Girardie, E. Coupez, P. Dequin, A. Cariou, T. Boulain, N. Brulé, J. Frat, P. Asfar, N. Pichon, M. Landais, G. Plantefeve, J. Quenot, J. Chakarian, M. Sirodot, S. Legriel, J. Letheulle, D. Thévenin, A. Desachy, A. Delahaye, V. Botoc, S. Vimeux, F. Martino, B. Giraudeau, J. Reignier   +28 more
semanticscholar   +1 more source

Association of Initial Illness Severity and Outcomes After Cardiac Arrest With Targeted Temperature Management at 36 °C or 33 °C

JAMA Network Open, 2020
Key Points Question What is the optimal target temperature for targeted temperature management (TTM) in comatose patients after cardiac arrest? Findings In a cohort study of 1319 patients, of whom 911 did not have severe cerebral edema or highly ...
C. Callaway, Patrick J Coppler, John W Faro, Jacob S. Puyana, P. Solanki, C. Dezfulian, A. Doshi, J. Elmer, A. Frisch, F. Guyette, M. Okubo, J. Rittenberger, A. Weissman   +12 more
semanticscholar   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

The association between hemoglobin concentration and neurologic outcome after cardiac arrest. [PDF]

, 2016
PURPOSE: The purpose of the study is to determine the association between hemoglobin concentration (Hgb) and neurologic outcome in postarrest patients. METHODS: We conducted a retrospective cohort study using the Penn Alliance for Therapeutic Hypothermia
Dodampahala, Kalani, Gaieski, David F., Goyal, Munish, Grossestreuer, Anne V., Johnson, Nicholas J., Perman, Sarah M., Rosselot, Babette   +6 more
core   +1 more source

Clinical Outcomes of In-Hospital Cardiac Arrest in COVID-19.

JAMA Internal Medicine, 2020
This case series examines outcomes of in-hospital cardiac arrest among patients with COVID-19.
Shrinjaya B Thapa, T. S. Kakar, C. Mayer, Dilip Khanal   +3 more
semanticscholar   +1 more source

Cardiac Arrest in Pigs With 48 hours of Post‐Resuscitation Care Induced by 2 Methods of Myocardial Infarction: A Methodological Description

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Systematic reviews have disclosed a lack of clinically relevant cardiac arrest animal models. The aim of this study was to develop a cardiac arrest model in pigs encompassing relevant cardiac arrest characteristics and clinically relevant post‐
Lauge Vammen, Cecilie Munch Johannsen, Andreas Magnussen, Amalie Povlsen, Søren Riis Petersen, Arezo Azizi, Bo Løfgren, Lars W. Andersen, Asger Granfeldt   +8 more
doaj   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Prehospital Randomised Assessment of a Mechanical Compression Device In Cardiac Arrest (PaRAMeDIC) Trial Protocol [PDF]

, 2010
BACKGROUND Survival after out-of-hospital cardiac arrest is closely linked to the quality of CPR, but in real life, resuscitation during prehospital care and ambulance transport is often suboptimal.
Anne Slowther, Charles Deakin, Chris McCabe, Gavin D Perkins, Jessica Horton, Malcolm Woollard, Matthew W Cooke, Ranjit Lall, Sarah E Lamb, Simon Gates, Tom Quinn   +10 more
core   +5 more sources

The Synergy of Artificial Intelligence and 3D Bioprinting: Unlocking New Frontiers in Precision and Tissue Fabrication

Advanced Functional Materials, EarlyView.
Advances in integrating artificial intelligence into 3D bioprinting are systematically reviewed here. Machine learning, computer vision, robotics, natural language processing, and expert systems are examined for their roles in optimizing bioprinting parameters, real‐time monitoring, quality control, and predictive maintenance.
Joao Vitor Silva Robazzi, Irem Deniz Derman, Deepak Gupta, Logan Haugh, Yogendra Pratap Singh, Vaibhav Pal, Yasar Ozer Yilmaz, Suihong Liu, Andre Luis Dias, Rogerio Andrade Flauzino, Ibrahim Tarik Ozbolat   +10 more
wiley   +1 more source

Assessing Variability in End-of-Life Intensity of Care After Out-of-Hospital Cardiac Arrest [PDF]

, 2017
Out of hospital cardiac arrest (OHCA) affects over 300,000 Americans per year.1 Many factors affect the outcomes and overall OHCA survival in a community; some of these include an individual’s characteristics such as age, co-morbid conditions ...
Carr, MD, MA, MS, Brendan G., Ferd, MD Candidate, Polina, Karp, MUSA, David, Zebrowski, PhD Candidate, Alexis   +3 more
core   +1 more source