Are Variants Causing Cardiac Arrhythmia Risk Factors in Sudden Unexpected Death in Epilepsy?
Sudden unexpected death in epilepsy (SUDEP) is the most common cause of premature mortality in individuals with epilepsy. Acute and adaptive changes in heart rhythm in epilepsy implicate cardiac dysfunction as a potential pathogenic mechanism in SUDEP ...
Lauren E. Bleakley +8 more
semanticscholar +1 more source
Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia
Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set daily rhythms in sinoatrial (SA)
Edward A. Hayter +12 more
semanticscholar +1 more source
Association of Air Pollution with Increased Incidence of Ventricular Tachyarrhythmias Recorded by Implanted Cardioverter Defibrillators [PDF]
Epidemiologic studies have demonstrated a consistent link between sudden cardiac deaths and particulate air pollution. We used implanted cardioverter defibrillator (ICD) records of ventricular tachyarrhythmias to assess the role of air pollution as a ...
David Q. Rich +9 more
core +2 more sources
Fasciculoventricular bypass tracts: Electrocardiographic and electrophysiologic features
Fasciculoventricular accessory pathways are rare variants of preexcitation. The differential diagnosis of fasciculoventricular accessory pathways from other preexcitation variants can be challenging.
Dimitrios Asvestas +8 more
doaj +1 more source
Increased baseline ECG R-R dispersion predicts improvement in systolic function after atrial fibrillation ablation. [PDF]
BackgroundAtrial fibrillation (AF) is associated with left ventricular (LV) systolic dysfunction which may improve after AF ablation. We hypothesised that increased ventricular irregularity, as measured by R-R dispersion on the baseline ECG, would ...
Buch, Eric +7 more
core +1 more source
CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core +2 more sources
The Emerging Role of Left Bundle Branch Area Pacing for Cardiac Resynchronisation Therapy
Cardiac resynchronisation therapy (CRT) reduces the risk of heart failure-related hospitalisations and all-cause mortality, as well as improving quality of life and functional status in patients with persistent heart failure symptoms despite optimal ...
Juan Carlos Diaz +11 more
doaj +1 more source
Which diagnostic tests are most useful in a chest pain unit protocol? [PDF]
Background The chest pain unit (CPU) provides rapid diagnostic assessment for patients with acute, undifferentiated chest pain, using a combination of electrocardiographic (ECG) recording, biochemical markers and provocative cardiac testing.
Angelini, K. +4 more
core +3 more sources
BackgroundThe 2005 Bethesda Conference Guidelines advise patients with long QT syndrome against competitive sports. We assessed cardiac event rates during competitive and recreational sports, and daily activities among treated long QT syndrome patients ...
Kristina D. Chambers +9 more
doaj +1 more source
Cardiac arrhythmia is associated with abnormal electrical activities of the heart, which can be reflected by altered characteristics of electrocardiogram (ECG).
Runnan He +6 more
semanticscholar +1 more source

