Although pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results
Michela Faggioni +10 more
doaj +1 more source
Infarct tissue characterization in implantable cardioverter-defibrillator recipients for primary versus secondary prevention following myocardial infarction: a study with contrast-enhancement cardiovascular magnetic resonance imaging [PDF]
Knowledge about potential differences in infarct tissue characteristics between patients with prior life-threatening ventricular arrhythmia versus patients receiving prophylactic implantable cardioverter-defibrillator (ICD) might help to improve the ...
Birgelen, C. von +7 more
core +3 more sources
A Computational Journey Toward an Optimal Design for Metamaterial Epicardial Passive Sleeves
Passive epicardial sleeves are evaluated in 3D in‐silico heart models to reveal how sleeve geometry, stiffness, anisotropy, and metamaterial architecture influence cardiac mechanics after myocardial infarction. A continuum‐to‐auxetic design exploration shows that region‐specific mechanical engagement can reduce infarct bulging and modulate torsional ...
Vahid Naeini +8 more
wiley +1 more source
SERCA is critical to control the Bowditch effect in the heart [PDF]
The Bowditch effect or staircase phenomenon is the increment or reduction of contractile force when heart rate increases, defined as either a positive or negative staircase.
Balcazar, Dario Emmanuel +6 more
core +2 more sources
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
Intracardiac Echocardiography-guided Left Atrial Appendage Occlusion
Left atrial appendage occlusion (LAAO) is a suitable alternative to oral anticoagulant therapy to prevent stroke in patients with AF. Most procedures are performed under transoesophageal echocardiography (TOE) guidance, which facilitates transseptal ...
Juan Carlos Diaz +9 more
doaj +1 more source
Background Atrial fibrillation (AF) is an increasingly prevalent public health problem and one of the most common causes of emergency department (ED) visits. We aimed to investigate the trends in ED visits and hospital admissions for AF.
Guy Rozen +7 more
doaj +1 more source
Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]
Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core
Medetomidine/midazolam/fentanyl narcosis alters cardiac autonomic tone leading to conduction disorders and arrhythmias in mice [PDF]
Philipp Tomsits +5 more
openalex +1 more source
Cardiac arrhythmia considerations of hormone cancer therapies
Breast and prostate cancers are among the most prevalent cancers worldwide. Oestradiol and progesterone are major drivers for breast cancer proliferation, and androgens for prostate cancer.
Mary C Barber +5 more
semanticscholar +1 more source

