A Heart for Diversity: Simulating Variability in Cardiac Arrhythmia Research
Frontiers in Physiology, 2018 In cardiac electrophysiology, there exist many sources of inter- and intra-personal variability. These include variability in conditions and environment, and genotypic and molecular diversity, including differences in expression and behavior of ion ...
H. Ni, S. Morotti, E. Grandi
semanticscholar +1 more source
Indeterminacy of Spatiotemporal Cardiac Alternans [PDF]
, 2007 Cardiac alternans, a beat-to-beat alternation in action potential duration (at the cellular level) or in ECG morphology (at the whole heart level), is a marker of ventricular fibrillation, a fatal heart rhythm that kills hundreds of thousands of people in the US each year.
arxiv +1 more source
Diabetes, obesity and metabolism, 2018 Hypoglycaemia is associated with increased cardiovascular risk among individuals with diabetes mellitus. It has been hypothesized that hypoglycaemia may trigger autonomic changes leading to increased cardiac arrhythmia risk.
C. Fitzpatrick +6 more
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Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs). [PDF]
, 2001 Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits.
Abbott, GW, Goldstein, SA
core
When the clock strikes: Modeling the relation between circadian rhythms and cardiac arrhythmias [PDF]
arXiv, 2016 It has recently been observed that the occurrence of sudden cardiac death has a close statistical relationship with the time of day, viz., ventricular fibrillation is most likely to occur between 12 am-6 am, with 6 pm-12 am being the next most likely period.
arxiv
Environmental Health, 2018 BackgroundThe relationship between particle matters (PMs) and cardiac arrhythmia has been investigated in numerous studies. However, evidence from developing countries is limited.
Q. Zheng +3 more
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Safety, Efficacy and Evidence Base for Use of the Subcutaneous Implantable Cardioverter Defibrillator [PDF]
, 2018 The trans-venous implantable cardioverter defibrillator (TV-ICD) is effective in treating life-threatening ventricular arrhythmia and reduces mortality in high-risk patients.
Adduci, Carmen +2 more
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Relating the spectrum of cardiac signals to the spatiotemporal dynamics of cardiac sources [PDF]
arXiv, 2013 An increasing number of studies use the spectrum of cardiac signals for analyzing the spatiotemporal dynamics of complex cardiac arrhythmias. However, the relationship between the spectrum of cardiac signals and the spatiotemporal dynamics of the underlying cardiac sources remains to date unclear.
arxiv
A clinical practice audit of management and outcomes of patients presenting with chest pain to the Medical Admissions Unit [PDF]
, 2009 Acute central chest pain accounts for a significant proportion of emergency medical admissions. If chest pain evaluation is systematic & risk-based, it may prevent unnecessary admissions.
Camilleri, Rene +2 more
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Efficacy of pimobendan in the prevention of congestive heart failure or sudden death in doberman pinschers with preclinical dilated cardiomyopathy (the PROTECT study) [PDF]
, 2012 <p>Background: The benefit of pimobendan in delaying the progression of preclinical dilated cardiomyopathy (DCM) in Dobermans is not reported.</p> <p>Hypothesis: That chronic oral administration of pimobendan to Dobermans with ...
Boswood, A. +15 more
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