Results 81 to 90 of about 227,292 (361)

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng   +11 more
wiley   +1 more source

Gelatin Methacryloyl Bioadhesive Improves Survival and Reduces Scar Burden in a Mouse Model of Myocardial Infarction

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Delivery of hydrogels to the heart is a promising strategy for mitigating the detrimental impact of myocardial infarction (MI). Challenges associated with the in vivo delivery of currently available hydrogels have limited clinical translation ...
Leon M. Ptaszek   +9 more
doaj   +1 more source

Fever Unmasked Brugada Syndrome in Pediatric Patient: A Case Report [PDF]

open access: yes, 2020
Introduction: Brugada syndrome is an arrhythmogenic disorder that is a known cause of sudden cardiac death. It is characterized by a pattern of ST segment elevation in the precordial leads on an electrocardiogram (EKG) due to a sodium channelopathy.Case ...
Brill, April   +2 more
core  

Enhancement of Gap Junction Function During Acute Myocardial Infarction Modifies Healing and Reduces Late Ventricular Arrhythmia Susceptibility [PDF]

open access: yes, 2016
Objectives: To investigate the effects of enhancing gap junction (GJ) coupling during acute myocardial infarction (MI) on the healed infarct scar morphology and late post-MI arrhythmia susceptibility.
Chowdhury, RA   +7 more
core   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

open access: yesAdvanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du   +9 more
wiley   +1 more source

Detection & Classification of Cardiac Arrhythmia [PDF]

open access: yes, 2017
The term Arrhythmia refers to any change from the normal sequence in the electrical impulses. It is also treated as abnormal heart rhythms or irregular heartbeats.
Bairagi, V. K., Jadhav, Chetan M.
core   +2 more sources

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

open access: yesAdvanced Science, Volume 12, Issue 17, May 8, 2025.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li   +21 more
wiley   +1 more source

How random is your heart beat? [PDF]

open access: yes, 2006
We measure the content of random uncorrelated noise in heart rate variability using a general method of noise level estimation using a coarse grained entropy.
Baselli   +30 more
core   +2 more sources

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

open access: yesAdvanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

A Novel real-time arrhythmia detection model using YOLOv8 [PDF]

open access: yesarXiv, 2023
In a landscape characterized by heightened connectivity and mobility, coupled with a surge in cardiovascular ailments, the imperative to curtail healthcare expenses through remote monitoring of cardiovascular health has become more pronounced. The accurate detection and classification of cardiac arrhythmias are pivotal for diagnosing individuals with ...
arxiv  

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