Results 151 to 160 of about 1,610,408 (351)

Management of Cardiovascular Health Issues in Turner Syndrome: Expert Insights and Expanded Recommendations From the 2024 Guideline Development Team

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote, Sheetal R. Patel, Kristian Havmand Mortensen, Isabel Witvrouwen, Anthonie Duijnhouwer, Nicole M. Brown, Jasmine Grewal, Kathryn C. Chatfield, Aaron T. Dorfman, Siddharth K. Prakash   +9 more
wiley   +1 more source

The Dialysis Procedure Triggers Autonomic Imbalance and Cardiac Arrhythmias: Insights from Continuous 14-day ECG Monitoring [PDF]

, 2019
Nichole M. Rogovoy, Stacey J. Howell, Tiffany Lee, Christopher Hamilton, Erick Andres Perez Alday, Muammar Kabir, Yin Li‐Pershing, Yanwei Zhang, Esther D. Kim, Jessica Fitzpatrick, Jose M. Monroy‐Trujillo, Michelle M. Estrella, Stephen M. Sozio, Bernard G. Jaar, Rulan S. Parekh, Larisa G. Tereshchenko   +15 more
openalex   +1 more source

Indeterminacy of Spatiotemporal Cardiac Alternans

, 2008
Cardiac alternans, a beat-to-beat alternation in action potential duration (at the cellular level) or in ECG morphology (at the whole heart level), is a marker of ventricular fibrillation, a fatal heart rhythm that kills hundreds of thousands of people ...
A. H. Nayfeh, D. M. Bers, D. S. Rubenstein, E. M. Cherry, G. W. Beeler, J. J. Fox, J. M. Pastore, J.J. Fox, M. Endo, M. L. Riccio, R. Plonsey, Xiaopeng Zhao   +11 more
core   +2 more sources

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K [PDF]

, 2018
SMO (Smoothened), the central transducer of Hedgehog signaling, is coupled to heterotrimeric Gi proteins in many cell types, including cardiomyocytes.
Al-Owais, Moza, Cheng, Lan, Covarrubias, Manuel, Koch, Walter J., Manning, David R., Peers, Chris, Riobo-Del Galdo, Natalia A   +6 more
core   +1 more source

Pimobendan alleviates myocyte apoptosis and fibrosis associated with mitral regurgitation by targeting endoplasmic reticulum stress

Animal Models and Experimental Medicine, EarlyView.
Mitral regurgitation (MR) causes volume overload and disrupts Ca2+ homeostasis. The volume overload leads to cardiac hypertrophy and fibrosis inferred from histopathological studies. Cardiac hypertrophy was identified by increased myocyte cross‐sectional area, left atrial‐to‐aortic root ratio, and left ventricular internal diameter at end‐diastole ...
Pakit Boonpala, Sushawadee Tongta, Nakkawee Saengklub, Vudhiporn Limprasutr, Sirinapa Srikam, Wilawan Ji‐au, Tussapon Boonyarattanasoonthorn, Yaowalak Panyasing, Sarawut Kumphune, Sarinee Kalandakanond‐Thongsong, Anusak Kijtawornrat   +10 more
wiley   +1 more source

COVID-19 and cardiac arrhythmias

Heart Rhythm, 2020
Anjali Bhatla, Michael M. Mayer, S. Adusumalli, Matthew C. Hyman, E. Oh, A. Tierney, Juwann Moss, Anwar A. Chahal, George Anesi, S. Denduluri, C. Domenico, Jeffrey S. Arkles, B. Abella, J. Bullinga, D. Callans, S. Dixit, A. Epstein, D. Frankel, Fermin C. García, Ramanan Kumareswaram, S. Nazarian, Michael P. Riley, P. Santangeli, R. Schaller, G. Supple, D. Lin, F. Marchlinski, R. Deo   +27 more
semanticscholar   +1 more source

Identification of New KCNT1‐Epilepsy Drugs by In Silico, Cell, and Drosophila Modeling

Annals of Neurology, EarlyView.
Objective Hyperactive KCNT1 potassium channels, caused by gain‐of‐function mutations, are associated with a range of epilepsy disorders. Patients typically experience drug‐resistant seizures and, in cases with infantile onset, developmental regression can follow.
Michael G. Ricos, Bethan A. Cole, Rashid Hussain, Grigori Y. Rychkov, Zeeshan Shaukat, Nadia Pilati, Stephen P. Muench, Katie J. Simmons, Leanne M. Dibbens, Jonathan D. Lippiat   +9 more
wiley   +1 more source

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

The Anatomical Record, EarlyView.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna, Donald B. Hoover, Logan G. Kirkland, Elizabeth H. Smith, Megan D. Poston, Stanley G. Peirce, Chloe G. Garbe, Tasha K. Phillips, Steven Cha, Shumpei Mori, Jaclyn A. Brennan, John Andrew Armour, Eric Rytkin, Igor R. Efimov, Olujimi A. Ajijola, Jeffrey L. Ardell, Kalyanam Shivkumar   +16 more
wiley   +1 more source

Mapping of low-voltage bridges with a high-density multipolar catheter in a child with atrioventricular nodal reentry tachycardia

HeartRhythm Case Reports, 2020
Fabrizio Drago, MD, Camilla Calvieri, MD, PhD, Greta Allegretti, BioMedEng, Massimo Stefano Silvetti, MD   +3 more
doaj   +1 more source