Results 301 to 310 of about 1,610,408 (351)
Effects of geranylgeranylacetone on diastolic and microvascular function in patients with heart failure with a preserved ejection fraction: A phase 2, randomized, placebo‐controlled, crossover trial
European Journal of Heart Failure, EarlyView.Abstract Aims
Heart failure with preserved ejection fraction (HFpEF) is a major healthcare burden with limited treatment options. Geranylgeranylacetone (GGA) has been shown to improve myocardial compliance and endothelial function in preclinical models.Soufiane Nassiri, Geert H.D. Voordes, Loek van Heerebeek, Daniël H. van Raalte, Marianne C. Verhaar, Daan J. Touw, Merle M. Krebber, Dirk J. Duncker, Etto C. Eringa, M. Louis Handoko, Adriaan A. Voors, on behalf of the RECONNEXT Consortium +11 morewiley +1 more sourceClinical and echocardiographic phenotype of cardiac wasting in patients with advanced cancer
European Journal of Heart Failure, EarlyView.Cardiac wasting‐associated cardiomyopathy in cancer patients. E/e', early diastolic filling velocity (E) over mitral annulus early diastolic tissue velocity (e'); GLS, global longitudinal strain; LV, left ventricular; LVEF, left ventricular ejection fraction; TAPSE, tricuspid annular plane systolic excursion.Markus S. Anker, Muhammad Shahzeb Khan, Anja Nikolski, Jan Porthun, Muhammad Sameer Arshad, Sara Hadzibegovic, Alessia Lena, Lucie Kretzler, Jonathan L. Hella, Marco Witkowski, Kathrin Rieger, Johann Ahn, Dominik P. Modest, Ulrich Keller, Lars Bullinger, Matthias Totzeck, Amir A. Mahabadi, Tienush Rassaf, Nikolaus Buchmann, Philipp Attanasio, Tanja Zeller, Mahir Karakas, Carlo G. Tocchetti, Ursula Wilkenshoff, John G. F. Cleland, Stephan von Haehling, Javed Butler, Ulf Landmesser +27 morewiley +1 more sourceAcute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides
European Journal of Heart Failure, EarlyView.Cancer patients presenting to the emergency department ED with dyspnoea. Among 2153 patients presenting to the ED with dyspnea, 473 (22.0%) had an active or past cancer. Acute heart failure (AHF) was the most common final diagnosis in both groups. Pneumonia and cancer‐related dyspnoea were more common in cancer patients.Paolo Bima, Desirée Wussler, Pedro Lopez‐Ayala, Maria Belkin, Albina Nowak, Xueting Lin, Ivo Strebel, Fabiana Sgueglia, Eleni Michou, Androniki Papachristou, Laureve Chollet, Codruta Popescu, Nikola Kozhuharov, Samyut Shrestha, Gabriela Kuster, Katharina Rentsch, Arnold Von Eckardstein, Mascha Binder, Felix Mahfoud, Tobias Breidthardt, Christian Mueller +20 morewiley +1 more sourceSimulation of cardiac arrhythmias in human induced pluripotent stem cell-derived cardiomyocytes. [PDF]
PLoS OneBommer T, Knierim M, Unsöld J, Riedl D, Stengel L, Paulus M, Körtl T, Liaw N, Maier LS, Streckfuss-Bömeke K, Sossalla S, Pabel S. +11 moreeuropepmc +1 more sourceClustering in dilated cardiomyopathy at initial evaluation: An effective tool for clinical stratification
European Journal of Heart Failure, EarlyView.Visual description of study design and main results. BBB, bundle branch block; ECG, electrocardiogram; MVA, major ventricular arrhythmia; SCD, sudden cardiac death. Abstract Aims
Dilated cardiomyopathy (DCM) has a highly variable presentation and disease course. Current stratification strategies are complex and require multimodality evaluation.Ilaria Gandin, Maria Perotto, Alessia Paldino, Giovanni Baj, Denise Zaffalon, Andrea Pezzato, Cinzia Crescenzi, Fabiana Romeo, Annamaria Martino, Francesca Fanisio, Federica Toto, Maddalena Rossi, Marta Gigli, Matteo Dal Ferro, Leonardo Calò, Gianfranco Sinagra, Marco Merlo +16 morewiley +1 more sourceAtrial cardiomyopathy: From healthy atria to atrial failure. A clinical consensus statement of the Heart Failure Association of the ESC
European Journal of Heart Failure, EarlyView.The diagnosis of atrial cardiomyopathy (AtCM) requires electrical atrial dysfunction, with evidence of either mechanical atrial dysfunction, atrial enlargement, or excessive atrial fibrosis. The diagnostic cut‐points presented are for standard electrocardiogram and echocardiogram studies (see Figure 1 for further detail).Jerremy Weerts, Otilia Țica, Julia Aranyo, Christian Basile, Angelina Borizanova‐Petkova, Josip Andjelo Borovac, Massimiliano Camilli, Martin Eichenlaub, Emiliano Fiori, Tim Van Loon, Coenraad Withaar, Diana Zakarkaitė, Matthias D. Zink, Marianna Adamo, Alberto Aimo, Elena Arbelo, Felipe Bisbal Van Bylen, Dimitrios T. Farmakis, Dobromir Dobrev, Jelena Čelutkienė, Michael Böhm, Andrew Coats, Marco Metra, Giuseppe Rosano, Frank Ruschitzka, Antoni Bayes‐Genis, Dipak Kotecha +26 morewiley +1 more source