Results 41 to 50 of about 169,604 (267)

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

BJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro, J. H. Kauppila, S. Markar, A. Johar, P. Lagergren   +4 more
wiley   +1 more source

Dynamic Expression of the Type 1 Brugada ECG Pattern During Tilt Table Testing Using Continuous High Precordial Lead Positioning

Diagnostics
Background/Objectives: The Type 1 Brugada ECG pattern (BrP1) fluctuates according to autonomic influences. Tilt table testing induces changes in both sympathetic and parasympathetic activity. It may provide insights into the dynamic behavior of BrP1 when
Eduardo Nolla Silva Pereira, Luciana Sacilotto, Tan Chen Wu, Gabrielle D’Arezzo Pessente, Nemer Luis Pichara, Denise Tessariol Hachul, Mauricio Ibrahim Scanavacca, Francisco Carlos da Costa Darrieux   +7 more
doaj   +1 more source

Frequency of Cardiac Arrhythmias in Hypertensive Patients

Pakistan Armed Forces Medical Journal, 2022
Objective: To determine the frequency of cardiac arrhythmias in hypertensive patients. Study Design: Analytical Cross -sectional study. Place & Duration of Study: Tertiary Cardiac Center, Lahore Pakistan from Jan 2021 to Dec2021. Methodology:
Muhammad Naeem Tariq, Naseer Ahmed Samore, Muhammad Humayoun Rashid, Sohail Aziz, Ghoza Chaudhery, Jahanzab Ali, Naseem Azad, Ahmad Noeman, Syeda Neelam Yamin Bukhari, Azhar Ali Chaudhry   +9 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source

Calmodulinopathy: Functional Effects of CALM Mutations and Their Relationship With Clinical Phenotypes

Frontiers in Cardiovascular Medicine, 2018
In spite of the widespread role of calmodulin (CaM) in cellular signaling, CaM mutations lead specifically to cardiac manifestations, characterized by remarkable electrical instability and a high incidence of sudden death at young age.
Beatrice Badone, Carlotta Ronchi, Maria-Christina Kotta, Luca Sala, Alice Ghidoni, Lia Crotti, Lia Crotti, Lia Crotti, Antonio Zaza   +8 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Heart arrhythmias and conduction disorders in patients with acromegaly: the role of cardiac magnetic resonance imaging

Терапевтический архив, 2020
Cardiovascular complications including arrhythmias and cardiac conduction disorders are one of the main reasons of high mortality rate in acromegaly, while they have not been well explored. Aim.To estimate arrhythmias frequency in acromegaly, identify
K. V. Melkozerov, E. G. Przhiyalkovskaya, N. V. Tarbaeva, A. A. Almaskhanova, M. D. Kuklina, P. A. Alferova, I. S. Gomova, L. A. Belousov, Z. E. Belaya, A. V. Vorontsov, V. Y. Kalashnikov   +10 more
doaj   +1 more source

Convolutional neural network for classification of eight types of arrhythmia using 2D time–frequency feature map from standard 12-lead electrocardiogram

Scientific Reports, 2021
Electrocardiograms (ECGs) are widely used for diagnosing cardiac arrhythmia based on the deformation of signal shapes due to changes in various heart diseases.
Da Un Jeong, Ki Moo Lim
doaj   +1 more source

Diagnostic yield and variant reassessment in the genes encoding Nav1.5 channel in Russian patients with Brugada syndrome

Frontiers in Pharmacology, 2022
Brugada syndrome (BrS) is an inherited cardiac arrhythmia characterized by ST-elevation, negative T-wave, and a high risk of sudden cardiac death (SCD) due to ventricular tachycardia.
Elena Zaklyazminskaya, Elena Zaklyazminskaya, Anna Shestak, Dmitry Podolyak, Vera Komoliatova, Leonid Makarov, Anna Novitskaya, Amiran Revishvili   +7 more
doaj   +1 more source