Results 221 to 230 of about 292,858 (349)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Mechanical circulatory support as a cornerstone in advanced heart failure and transplantation. [PDF]

Front Cardiovasc Med
Braga M, Pinho AI, Jorde U, González-Costello J.   +3 more
europepmc   +1 more source

Shear stress, energy losses, and costs: a resolved dilemma of pulsatile cardiac assist devices. [PDF]

Biomed Res Int, 2014
Nour S, Liu J, Dai G, Carbognani D, Yang D, Wu G, Wang Q, Chachques JC.   +7 more
europepmc   +1 more source

Change of Coronary Flow by Continuous-Flow Left Ventricular Assist Device With Cardiac Beat Synchronizing System (Native Heart Load Control System) in Acute Ischemic Heart Failure Model

, 2012
Akihide Umeki, Takashi Nishimura, Masahiko Ando, Yoshiaki Takewa, Kenji Yamazaki, Shunei Kyo, Minoru Ōno, Tomonori Tsukiya, Toshihide Mizuno, Yoshiyuki Taenaka, Eisuke Tatsumi   +10 more
openalex   +2 more sources

Engineered Multifunctional Hydrogel Delivering Novel CBX7 Inhibitor Modulates Cuproptosis Via Liquid–Liquid Phase Separation to Restore Cardiac Function in Aged Myocardial Infarction

Advanced Science, EarlyView.
An age‐adapted therapy pairs δ‐Amyrenone, a CBX7 inhibitor, with an alginate hydrogel (CSAδ) to rescue infarcted elderly hearts. CSAδ disrupts CBX7–ATP7A liquid–liquid phase separation, restores ATP7A trafficking and copper efflux, suppresses cuproptosis, supplies oxygen, scavenges ROS, promotes M2 polarization, supports angiogenesis, and enhances ...
Jun Liu, Peng Qu, Jiao Shi, Tingting Liang, Yao Gu, Xue Li, Cui Ma, Danyang Zhao, Feila Liu, Qi Liang, Panke Cheng, Qian Lei   +11 more
wiley   +1 more source

Atrial fibrillation in continuous flow-left ventricular assist device (CF-LVAD) patients: impact on pathophysiology. [PDF]

J Artif Organs
Nair N, Du D, Mahesh B.
europepmc   +1 more source

A Novel Cardiac Coordinate Modeling System for Three Dimensional Quantification of Inflow Cannula Malposition in HeartMate II Left Ventricular Assist Device Implantation [PDF]

, 2016
Brian Lima, Onur Dur, Joyce Chuang, Themistokles Chamogeorgakis, David J. Farrar, Kartik S. Sundareswaran, Shelley Hall, G.V. Gonzalez-Stawinski   +7 more
openalex   +1 more source

Impact of age, sex, therapeutic intent, race and severity of advanced heart failure on short-term principal outcomes in the MOMENTUM 3 trial [PDF]

, 2018
et al,, Itoh, Akinobu
core   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Echocardiographic assessment of a novel blood-guiding accessory for left ventricular assist devices in swine. [PDF]

Interdiscip Cardiovasc Thorac Surg
Galbas MC, Meissner F, Straky H, Reuter J, Schimmel M, Czerny M, Bothe W.   +6 more
europepmc   +1 more source