Results 181 to 190 of about 718,690 (296)

Pulmonary pulsatility quantified by electrical impedance tomography in severe acute respiratory distress syndrome patients undergoing extracorporeal membrane oxygenation support. [PDF]

Ann Intensive Care
Leali M, Spinelli E, Giani M, Pavlovsky B, Di Pierro M, Crotti S, Lissoni A, Foti G, Grasselli G, Mauri T, Slobod D.   +10 more
europepmc   +1 more source

Bifunctional Artificial Enzymes‐Loaded Microgels With LOX‐ and CAT‐Like Activities for Metabolic Reprogramming and Scarless Wound Repair

Advanced Science, EarlyView.
A bifunctional lactate oxidase‐like and catalase‐like artificial enzyme (Metazyme) is integrated into a rod‐shaped microgel (MetaRgel) to enable cascade lactate oxidation and oxygen regeneration. By reprogramming the wound metabolic microenvironment, MetaRgel alleviates excessive lactate accumulation, oxidative stress, hypoxia, and inflammation ...
Yongyuan Kang, Pai Peng, Liang Song, Qiaoxuan Wang, Zilong Zhong, Dongchao Qiu, Yunfan Liu, Kefei Zhao, Xiaofei Dong, Changyou Gao   +9 more
wiley   +1 more source

Simultaneous Assessment of Skeletal Muscle Energetics and Blood Flow During Dynamic Exercise by Interleaved ³¹P-MRS/¹H-MRI. [PDF]

Magn Reson Med
Samuel TJ, Ganji SK, Goldenberg JR, Lewsey SC, Hays AG, Weiss RG, Schär M.   +6 more
europepmc   +1 more source

The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses [PDF]

, 2005
A.L. Raisis, Akaike, Bennett, Berne, Borow, Branson, Brunson, DiCorte, Diggle, Dunlop, Dyson, Johnston, K Rogers, K.J. Blissitt, L.E. Young, Little, Lunn, Madan, Peters, Raisis, Raisis, Searle, Seymour, Singer, Singer, Singer, Steffey, Steffey, Steffey, Steffey, Steffey, Taylor, V Adams, Veenman, W Henley, Wagner, Wallmeyer, Young, Young   +38 more
core   +1 more source

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Hemodynamic impact of acute liver injury on cardiac function: An in silico study via a closed-loop cardiovascular model. [PDF]

PLoS Comput Biol
Zhang J, Li Z, Feng L, Zhang J, Bai T, Jiang W.   +5 more
europepmc   +1 more source

First Generation Proteolysis Targeting Chimeras (PROTACs) for the Treatment of Progeria

Advanced Science, EarlyView.
We report the first PROTACs designed to degrade progerin, introducing a novel therapeutic approach for progeria. The best compound, UCM‐18142, significantly reduces progerin levels and improves key disease phenotypes in patient‐derived cells and in the LmnaG609G/G609G mouse model, paving the way for new treatment strategies targeting the root cause of ...
Jon Macicior‐Michelena, Marcelino Telechea, Daniel Fernández, Alba García‐Martín, Ángeles Canales, Silvia Ortega‐Gutiérrez   +5 more
wiley   +1 more source

A new anesthesia management for giant intracardiac and intravenous leiomyomatosis. [PDF]

J Cardiothorac Surg
Li K, Yuan M, Liao L, Li C.
europepmc   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Intra-aortic adrenaline titration during cardiac arrest. [PDF]

Scand J Trauma Resusc Emerg Med
Manning JE, Barnard EBG, Barratt J, Rees PSC.   +3 more
europepmc   +1 more source