Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Exercise-Induced ECG Abnormalities in Pediatric Pectus Excavatum: Evidence of Right Ventricular Compression Beyond the Haller Index. [PDF]
Guerrier K +7 more
europepmc +1 more source
ABSTRACT The survival of infants and children with complex medical conditions continues to increase, underscoring the need to quantify technology dependence more effectively. Existing measures emphasize mortality risk and fail to capture the burden of ongoing technological support.
Ashlee J. Vance +5 more
wiley +1 more source
Premature Ventricular Complexes With 2 QRS Morphologies: Cardiac Crux Insights and an Endocardial Ablation Strategy. [PDF]
Vo TD, Nguyen MN, Lin CY.
europepmc +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source
Coronary Ectasia and Ventricular Arrhythmia in a Patient With Prior Tick Exposure and Borrelia burgdorferi IgG Seroreactivity: A Case Report. [PDF]
Grigorov RK +3 more
europepmc +1 more source
ABSTRACT Objective This study evaluates the procedural characteristics, complications, and outcomes of intrauterine transfusion (IUT) for fetal anemia caused by parvovirus B19 infection during the 2023–2024 epidemic in Northwestern Europe. Method This multicenter observational study included all fetuses undergoing IUT for proven parvovirus B19‐induced ...
Banu Özbakir +6 more
wiley +1 more source
Fetal Intracranial Hemorrhage: What to Tell Expecting Parents?
ABSTRACT To review the classification, epidemiology, etiology, prenatal diagnostic approach, and neurodevelopmental outcomes of fetal intracranial hemorrhage (ICH), and to provide clinicians with a practical, fetal‐specific framework for investigating and counseling families facing this diagnosis.
Shiri Shinar, Yada Kunpalin, Elka Miller
wiley +1 more source
Expert consensus on clinical trial design guidelines for FLASH radiotherapy
• FLASH radiotherapy has emerged as a transformative technology due to the underlying FLASH effect. • As FLASH radiotherapy moves toward clinical application, establishing standardized trial design principles is critical. • This expert consensus provides a roadmap for rigorous clinical evaluation of FLASH radiotherapy, accelerating safe translation of ...
Hui Luo +9 more
wiley +1 more source
Catheter ablation of premature ventricular complexes originating from papillary muscles using dual-energy lattice-tip focal catheter [PDF]
Schlosser F +8 more
europepmc +2 more sources

