Cardiac contusion, usually caused by blunt chest trauma, has been recognized with increased frequency over the past decades. Traffic accidents are the most frequent causes of cardiac contusion resulting from a direct blow to the chest.
S. Zerbo +6 more
doaj +1 more source
Prolonged PR interval, first-degree heart block and adverse cardiovascular outcomes: a systematic review and meta-analysis [PDF]
Objective: First-degree atrioventricular block is frequently encountered in clinical practice and is generally considered a benign process. However, there is emerging evidence that prolonged PR interval may be associated with adverse outcomes. This study
Barker, Diane +11 more
core +1 more source
Background Conduction system disease may represent an early manifestation of underlying structural heart disease, including infiltrative disorders.
Jeremy William +12 more
doaj +1 more source
Recovery of complete left bundle branch block in dilated cardiomyopathy after optimal heart failure treatment: a case report [PDF]
Complete left bundle branch block (CLBBB) is a significant cardiac conduction abnormality often associated with dilated cardiomyopathy (DCM). This case report highlights the improvement in CLBBB and symptom relief through reverse cardiac remodeling in a ...
Geum Ko, Jae-Geun Lee
doaj +1 more source
Congenital and childhood atrioventricular blocks: pathophysiology and contemporary management [PDF]
Atrioventricular block is classified as congeni- tal if diagnosed in utero, at birth, or within the first month of life. The pathophysiological process is believed to be due to immune-mediated injury of the conduction system, which occurs as a result
A Ambrosi +110 more
core +3 more sources
Erbb2 is required for cardiac atrial electrical activity during development.
The heart is the first organ required to function during embryonic development and is absolutely necessary for embryo survival. Cardiac activity is dependent on both the sinoatrial node (SAN), which is the pacemaker of heart's electrical activity, and ...
Gennadiy Tenin +7 more
doaj +1 more source
Ion channels: structural basis for function and disease. [PDF]
Ion channels are ubiquitous proteins that mediate nervous and muscular function, rapid transmembrane signaling events, and ionic and fluid balance. The cloning of genes encoding ion channels has led to major strides in understanding the mechanistic basis
Goldstein, SA
core +1 more source
Familial Dilated Cardiomyopathy and Isolated Left Ventricular Noncompaction Associated With Lamin A/C Gene Mutations [PDF]
[Abstract] LMNA mutations have been associated with familial or sporadic dilated cardiomyopathy (DC), with or without conduction system disease. We studied the LMNA gene in 67 consecutive patients with DC (18 had familial DC, 17 had possible familial DC,
Bouzas-Zubeldia, Beatriz +10 more
core +2 more sources
Comportamiento de las arritmias cardiacas y los trastornos de conducción en una Unidad de Cuidados Coronarios. Characterization of cardiac arrhythmias and dysfunction of the conduction system at Intensive Coronary Care Unit. [PDF]
Introduction Cardiac arrhythmias and dysfunctions of the conduction system constitute animportant group among cardiac diseases. However, its prevalence in hospitalizedpatients has not been well established.Objective Characterization of cardiac ...
Geovedy Martínez García +4 more
doaj
Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]
Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro +5 more
core +1 more source

