Results 101 to 110 of about 369,292 (356)

The effectiveness of the cardiac resynchronization in a patient with ischemic cardiomyopathy [PDF]

open access: yes, 2018
Cardiac resynchronization therapy (CRT) in multiple and large trials has been demonstrated to improve symptoms and decrease hospitalization and mortality of patients when used in addition to optimal medical therapy.
Bătăiosu, Constantin   +5 more
core   +4 more sources

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey   +2 more
wiley   +1 more source

Basilar Artery Occlusion Stroke Managed With Tenecteplase Versus Alteplase Before Endovascular Treatment (BAO‐TNK)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To compare the effectiveness and safety of tenecteplase (TNK) versus alteplase (TPA) in patients with basilar artery occlusion prior to endovascular treatment (EVT). Methods In this retrospective multicenter study (BAO‐TNK), we analyzed consecutive BAO patients from 14 U.S.
Rahul R. Karamchandani   +38 more
wiley   +1 more source

Conduction defects and arrhythmias in mdx mice are not associated with a degeneration of the cardiac Purkinje network

open access: yesFrontiers in Physiology
Duchenne muscular dystrophy (DMD) is a severe X-chromosomal disease characterised by progressive muscle weakness and degeneration. Cardiac involvement is inevitable in DMD patients and ventricular arrhythmias are a high-risk factor for mortality in these
Juliette Vahdat   +4 more
doaj   +1 more source

Influence of cardiac tissue anisotropy on re-entrant activation in computational models of ventricular fibrillation

open access: yes, 2009
The aim of this study was to establish the role played by anisotropic diffusion in (i) the number of filaments and epicardial phase singularities that sustain ventricular fibrillation in the heart, (ii) the lifetimes of filaments and phase singularities,
Clayton, R.H.
core   +1 more source

HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity

open access: yesPLoS Genetics, 2017
HSPB7 is a member of the small heat-shock protein (HSPB) family and is expressed in the cardiomyocytes from cardiogenesis onwards. A dramatic increase in HSPB7 is detected in the heart and blood plasma immediately after myocardial infarction ...
Wern-Chir Liao   +4 more
semanticscholar   +1 more source

Persistent Leukoencephalopathy Following H1N1 Infection Associated With a Novel MYRF Variant (p.Gly735Asp)

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Mutations in myelin regulatory factor (MYRF) are linked to demyelinating disorders. We report a 38‐year‐old male who developed acute symmetric leukoencephalopathy mimicking a stroke following an influenza A virus infection. While clinical symptoms markedly improved with corticosteroids, MRI revealed persistent white matter lesions, contrasting
Jinghan Hu   +5 more
wiley   +1 more source

Current Advance, Challenges and Future Perspectives of Conduction System Pacing

open access: yesReviews in Cardiovascular Medicine
Existing techniques for pacing the right ventricle and providing cardiac resynchronization therapy through biventricular pacing are not effective in restoring damage to the conduction system.
Tong-yu Wang   +6 more
doaj   +1 more source

Virtual cardiac monolayers for electrical wave propagation [PDF]

open access: yes, 2017
The complex structure of cardiac tissue is considered to be one of the main determinants of an arrhythmogenic substrate. This study is aimed at developing the first mathematical model to describe the formation of cardiac tissue, using a joint in silico ...
Agladze, Konstantin   +3 more
core   +1 more source

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