Results 141 to 150 of about 139,869 (296)

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source

Roles of cardiac neural crest cells in cardiovascular development and associated congenital defects-an integrated review

Translational Research in Anatomy
The development of the cardiovascular system is a highly intricate process that encompasses various types of cells and communication pathways. During embryonic development, specific cells differentiate and organize to form complex structures of the heart
Worku Abie Liyew, Fentahun Adane, Amsalu Taye Wondemagegn, Binalfew Tsehay, Yikeber Argachew Deml, Hussen Muhidin Abdu, Zelalem Animaw   +6 more
doaj   +1 more source

Autopsy for Medical Diagnostics: Finding the Cause of Sudden Unexpected Death through Investigation of the Cardiac Conduction System by Serial Sections. [PDF]

Diagnostics (Basel), 2023
Ottaviani G, Ramos SG.
europepmc   +1 more source

Preliminary Study of a Ninj1‐Loaded Bimodal Ultrasound/NIR Fluorescence Targeted Molecular Probe for Diagnosing Early‐Stage Inflammation in Coronary Microvascular Dysfunction

Advanced Healthcare Materials, EarlyView.
Coronary microvascular dysfunction (CMD) targeting remains a challenge for precise diagnosis. This work presents a dual‐modal nanoprobe (T‐IR780‐NBs) that combines ultrasound contrast with near‐infrared fluorescence. This technology utilizes proteomics‐derived antibodies that specifically localize to inflamed and injured cardiac tissue, enabling ...
Xiaohui Xu, Lina Guan, Baihetiya Tayier, Chen Yuan, Shangke Chen, Qi Shi, Yuming Mu   +6 more
wiley   +1 more source

Conduction system pacing in a patient with persistent left superior vena cava and absent right superior vena cava: a case report

Journal of Medical Case Reports
Background Physiologic pacing is increasingly used as an alternative when there is a failure in cardiac resynchronization therapy, with more challenging situations expected consequently.
Oriol Rodriguez-Queralto, Carlos Gonzalez-Matos, Fatima Zaraket, Benjamin Casteig, Jesús Jimenez-Lopez, Ermengol Valles   +5 more
doaj   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Association of atrial tachyarrhythmia, heart block, and right ventricular dysfunction: a case report and review of literature

Journal of Medical Case Reports
Background The association of right ventricular dysfunction, atrial tachyarrhythmias, and cardiac conduction system disease is rarely reported in literature. Previous case reports include right ventricular dysfunction associated with sudden cardiac death
Mohamed Muharram, Sherien Samy, Ahmed Shaaban, Ahmed El-Damaty   +3 more
doaj   +1 more source

GOing Forward With the Cardiac Conduction System Using Gene Ontology. [PDF]

Front Genet, 2022
Chloe Li KY, Cook AC, Lovering RC.
europepmc   +1 more source

Cardiac Resynchronization Therapy and Conduction System Pacing

Journal of Clinical Medicine
Left bundle branch block (LBBB), initially described in the early 20th century, has become increasingly recognized as one of the leading causes of advanced heart failure (HF). In addition to rapidly growing data on guideline-directed medical therapy, cardiac resynchronization therapy (CRT) via transvenous coronary sinus lead has been the gold-standard ...
Thomas Garvey O’Neill, Takahiro Tsushima, Bhupendar Tayal   +2 more
openaire   +2 more sources

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source