Results 171 to 180 of about 141,036 (291)

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

A novel transgenic Cre allele to label mouse cardiac conduction system. [PDF]

Dev Biol, 2021
Kahr PC, Tao G, Kadow ZA, Hill MC, Zhang M, Li S, Martin JF.   +6 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Cardiac conduction system malformations in heterotaxy result from dysregulated Pitx2 expression. [PDF]

JCI Insight
Joo K, Matsuoka R, Kitajima K, Yashiro K, Shiose A, Tominaga R, Shen MM, Oki S, Meno C.   +8 more
europepmc   +1 more source

Diagnosing a wide complex tachycardia using basic electrophysiologic properties of the cardiac conduction system. [PDF]

J Arrhythm, 2022
Siroky GP, Mehta D.
europepmc   +1 more source

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Editorial: Advancing our understanding of the cardiac conduction system to prevent arrhythmias. [PDF]

Front Physiol
Vigmond EJ, Bayer J.
europepmc   +1 more source

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

Radiation exposure and clinical validation of autosegmentation models for the supraventricular cardiac conduction system in breast cancer radiotherapy: an institutional perspective. [PDF]

Front Oncol
Zhang Y, Han X, Chi Z, Zhao Z, Wang F, Liu D, Han R.   +6 more
europepmc   +1 more source

Sudden Unexpected Death Associated with Arrhythmogenic Cardiomyopathy: Study of the Cardiac Conduction System. [PDF]

Diagnostics (Basel), 2021
Ottaviani G, Alfonsi G, Ramos SG, Buja LM.   +3 more
europepmc   +1 more source