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The LMNA gene, which encodes the nuclear envelope protein lamin A/C, is considered to be the most common autosomal disease gene associated with familial dilated cardiomyopathy. To date, each mutation of the LMNA gene has been associated with a specific disease phenotype.
Wenting Chen +4 more
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Cardiac transthyretin amyloidosis in patients with conduction system disease
European Heart JournalAbstract Background/Introduction Cardiac amyloidosis (CA) is characterized by extracellular deposition of misfolded proteins in the heart. The data suggest that cardiac amyloidosis is underappreciated as a cause of common cardiac diseases or syndromes.
J Pudich +9 more
openaire +1 more source
Progress in Cardiovascular Diseases, 2005
Throughout the cardiac conduction system of each heart there were numerous destructive lesions including focal inflammatory infiltration with lymphocytes and in neighboring regions extensive focal fibrotic degeneration. These lesions involved myocytes, nerves and blood vessels.
Thomas N, James +2 more
openaire +2 more sources
Throughout the cardiac conduction system of each heart there were numerous destructive lesions including focal inflammatory infiltration with lymphocytes and in neighboring regions extensive focal fibrotic degeneration. These lesions involved myocytes, nerves and blood vessels.
Thomas N, James +2 more
openaire +2 more sources
European Journal of Nuclear Medicine and Molecular Imaging, 2015
Cardiac sarcoidosis (CS) is a cause of conduction system disease (CSD). (18)F-Fluorodeoxyglucose-positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) are used for detection of CS. The relative diagnostic value of these has not been well studied.
Hiroshi, Ohira +25 more
openaire +2 more sources
Cardiac sarcoidosis (CS) is a cause of conduction system disease (CSD). (18)F-Fluorodeoxyglucose-positron emission tomography (FDG PET) and cardiac magnetic resonance (CMR) are used for detection of CS. The relative diagnostic value of these has not been well studied.
Hiroshi, Ohira +25 more
openaire +2 more sources
[Steinert's disease with cardiac arrhythmia. Morphological findings in the heart conduction system].
Archivos del Instituto de Cardiologia de Mexico, 1975This is a case report of a 63-year-old man with myotonic dystrophy in whom an ECG showed atrial flutter, complete A-V block, idioventricular rhythm with image of left bundle branch block and giant, wide and negative "T-U" waves. The microscopic study of the conduction system showed slight fibrosis of the SAN, fatty infiltration and cellular atrophy of ...
R, Drut, O, Velasco Vela, L, Maljar
openaire +1 more source
Novartis Foundation symposium, 2004
To unravel the complex disease phenotype of heart failure, we are utilizing an integrative approach employing genomics, physiology, and mouse genetics to identify nodal pathways for specific physiological end points such as myocyte stretch activation responses, contractility and electrical conduction.
Tara R, St Amand +2 more
openaire +1 more source
To unravel the complex disease phenotype of heart failure, we are utilizing an integrative approach employing genomics, physiology, and mouse genetics to identify nodal pathways for specific physiological end points such as myocyte stretch activation responses, contractility and electrical conduction.
Tara R, St Amand +2 more
openaire +1 more source
The role of cardiac rehabilitation in improving cardiovascular outcomes
Nature Reviews Cardiology, 2021Rodney Taylor +2 more
exaly
Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management
Ca-A Cancer Journal for Clinicians, 2016Giuseppe Curigliano +2 more
exaly

