Results 281 to 290 of about 178,867 (336)

Prevalence, Incidence, and Impact on Mortality of Conduction System Disease in Transthyretin Cardiac Amyloidosis

The American Journal of Cardiology, 2020
Transthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized infiltrative cardiomyopathy in which conduction system disease is common. The aim of our study was to define the incidence and prevalence of high-grade atrioventricular (AV) block requiring pacemaker implantation in our quaternary referral center.
Eoin Donnellan, Oussama M. Wazni, Walid I. Saliba, Mazen Hanna, Mohamed Kanj, Divyang Patel, Bryan Wilner, Arshneel Kochar, Wael A. Jaber   +8 more
semanticscholar   +4 more sources

The cardiac conduction system: History, development, and disease

Current Topics in Developmental Biology
The heart is the first organ to form during embryonic development, establishing the circulatory infrastructure necessary to sustain life and enable downstream organogenesis. Critical to the heart's function is its ability to initiate and propagate electrical impulses that allow for the coordinated contraction and relaxation of its chambers, and thus ...
Carissa Lee, Sidra Xu, Tahmina Samad, William R. Goodyer, Alireza Raissadati, Paul V. Heinrich, Sean M. Wu   +6 more
semanticscholar   +4 more sources

Hereditary Long QT Syndrome Associated with Cardiac Conduction System Disease

Pacing and Clinical Electrophysiology, 1989
This report describes the cardiac conduction abnormalities, detected by invasive electrophysiological study, in two identical siblings with symptomatic congenital long QT syndrome. Both patients had evidence of intra‐Hisian conduction delay in response to programmed atrial stimulation and pacing induced infranodal block was seen in one of the two ...
Arnold J. Greenspon, Gregory A. Kidwell, LINDA D. BARRASSE, Scott E. Hessen, Michael Giudici   +4 more
semanticscholar   +4 more sources

Symptomatic Conduction System Disease in Cardiac Amyloidosis

The American Journal of Cardiology, 1997
Symptomatic conduction system disease in cardiac amyloidosis and its management has been reported infrequently. We report our experience of patients with amyloidosis having symptomatic conduction system disease requiring permanent pacemaker implantation.
Verghese Mathew, Lyle J. Olson, Morie A. Gertz, David L. Hayes   +3 more
semanticscholar   +4 more sources

PRKAG2 cardiac syndrome: familial ventricular preexcitation, conduction system disease, and cardiac hypertrophy

Current Opinion in Cardiology, 2002
Genetic studies of families with inherited cardiac rhythm disturbances have established a molecular basis for ventricular arrhythmogenic disorders. Genes responsible for the long QT syndrome, Brugada syndrome, and polymorphic ventricular tachycardia have been identified.
Michael H. Gollob, Martin S. Green, Anthony Tang, Robert J. Roberts   +3 more
semanticscholar   +4 more sources

Sodium channel kinetic changes that produce Brugada syndrome or progressive cardiac conduction system disease

American Journal of Physiology-Heart and Circulatory Physiology, 2006
Some mutations of the sodium channel gene NaV1.5 are multifunctional, causing combinations of LQTS, Brugada syndrome and progressive cardiac conduction system disease (PCCD). The combination of Brugada syndrome and PCCD is uncommon, although they both result from a reduction in the sodium current.
Zhu-Shan Zhang, Joseph V. Tranquillo, Valentina Neplioueva, Nenad Bursac, Augustus O. Grant   +4 more
semanticscholar   +4 more sources

Conduction System Disease in Fetuses Evaluated for Irregular Cardiac Rhythm

Fetal Diagnosis and Therapy, 2006
<i>Objectives:</i> To determine the prevalence of 1st and 2nd degree AV block in fetuses with an irregular cardiac rhythm, and to summarize outcome of these pregnancies. <i>Background:</i> The diagnosis of irregular cardiac rhythm or ‘skipped beats’ includes isolated ectopy that resolves spontaneously.
Bettina F. Cuneo, Janette F. Strasburger, Ronald T. Wakai, Marc Ovadia   +3 more
semanticscholar   +4 more sources

A novel mutation of the LMNA gene in a family with dilated cardiomyopathy, conduction system disease, and sudden cardiac death of young females

Molecular and Cellular Biochemistry, 2013
The LMNA gene, which encodes the nuclear envelope protein lamin A/C, is considered to be the most common autosomal disease gene associated with familial dilated cardiomyopathy. To date, each mutation of the LMNA gene has been associated with a specific disease phenotype.
Wenting Chen, Jianhua Huo, Aiqun Ma, Ling Bai, Ping Liu   +4 more
semanticscholar   +5 more sources

Diminished tyrosine hydroxylase immunoreactivity in the cardiac conduction system and myocardium in Parkinson’s disease: an anatomical study

Acta Neuropathologica, 2009
Clinical and autopsy studies have consistently reported cardiac sympathetic dysfunction in the left ventricular wall in patients with Parkinson's disease (PD). Whether the nerve fibers of the cardiac conduction system or the atrial walls are equally affected in this disease process has not yet been well documented.
Estifanos Ghebremedhin, Kelly Del Tredici, J. William Langston, Heiko Braak   +3 more
semanticscholar   +5 more sources

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Can Cardiac Conduction System Disease Be Prevented?

JAMA Internal Medicine, 2016
Cardiac conduction system disorders on the electrocardiogram (ECG) are common. Left bundle branch block (LBBB) is associated with adverse outcomes, and variants previously considerednormal, suchas rightbundlebranchblock (RBBB),1 left anterior fascicularblock,2orPR intervalprolongation,3may also portend morbidity andmortality. At present, no paradigm to
Sanjiv M, Narayan, Tina, Baykaner, David J, Maron   +2 more
openaire   +3 more sources