Results 91 to 100 of about 1,199,408 (314)

Synergistic Osteogenesis After Co‐Administration of cmRNAs Encoding BMP‐2 and BMP‐7 Utilizing a Transcript‐Activated Matrix

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates that the dual delivery of BMP‐2/‐7 coding cmRNAs for bone healing is demonstrated as feasible, safe, and highly osteogenic. Compared to single BMP‐2 or BMP‐7 cmRNAs, the combination enhances the production of both mineral and organic components of the extracellular matrix when delivered using a collagen‐HA scaffold, supporting ...
Claudia Del Toro Runzer   +7 more
wiley   +1 more source

Reply to the Comment on: Marco Cirillo The Memory of the Heart. J. Cardiovasc. Dev. Dis. 2018, 5, 55

open access: yesJournal of Cardiovascular Development and Disease, 2018
I was disappointed by Anderson’s comment on my recent review, a comment that I think derives from a too quick reading of the article. [...]
Marco Cirillo
doaj   +1 more source

TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice [PDF]

open access: yes, 2017
Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced maladaptive ...
Birnbaumer, Lutz   +10 more
core   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

open access: yesAdvanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth   +2 more
wiley   +1 more source

Stellate Ganglion Blockade for Electrical Storm and Early Outcomes: A Case Series in patients with Ischemic Heart Disease

open access: yesIndian Pacing and Electrophysiology Journal, 2022
Anand Y. Pasula   +2 more
doaj   +1 more source

The Memory of the Heart

open access: yesJournal of Cardiovascular Development and Disease, 2018
The embryological development of the heart is one of the most fascinating phenomena in nature and so is its final structure and function. The various ontogenetic passages form the evolutive basis of the final configuration of the heart. Each key step can
Marco Cirillo
doaj   +1 more source

Congestive cardiac failure [PDF]

open access: yes, 2006
'Common. costly and deadly'. This in a nutshell describes the condition we traditionally refer to as Cardiac Failure. Indeed 'Circulatory failure' would be a more appropriate term as it is a combination of factors that involve not only the heart but ...
Fenech, Albert
core  

Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis [PDF]

open access: yes, 2013
Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘
Barr, D. A.   +5 more
core   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou   +4 more
wiley   +1 more source

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